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网站主页 IDURONATE 2 SULFATASE/IDS, HUMAN, 重组蛋白 (HIS) Iduronate 2 sulfatase/IDS, Human, 重组蛋白 (His)
  • Iduronate 2 sulfatase/IDS, Human, 重组蛋白 (His)|TMPY-00828|TargetMol

Iduronate 2 sulfatase/IDS, Human, 重组蛋白 (His)|TMPY-00828|TargetMol

Iduronate 2 sulfatase/IDS Protein, Human, Recombinant (His)
￥22500 500μg 起订
上海 更新日期：2026-05-08

TargetMol 中国（陶术生物）

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联系人：邵经理
电话：400-821-0310拨打
手机：15002144251 拨打
邮箱：xuexiang.shao@tsbiochem.com

产品详情:

中文名称：
Iduronate 2 sulfatase/IDS, Human, 重组蛋白 (His)
英文名称：
Iduronate 2 sulfatase/IDS Protein, Human, Recombinant (His)
品牌：
TargetMol
产地：
美国
保存条件：
Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months
纯度规格：
96.60%
产品类别：
抑制剂
种属：
Human
表达系统：
HEK293 Cells
蛋白长度：
A DNA sequence encoding human IDS precursor (NP_000193.1) (Met 1-Pro 550) was expressed with a C-terminal polyhistidine tag. Predicted N terminal: Ser 26
标签：
C-His
货号：
T011|TMPY-00828

Product Introduction

Bioactivity

名称Iduronate 2 sulfatase/IDS Protein, Human, Recombinant (His)
描述Iduronate 2-Sulfatase, also known as IDS, is a member of the highly conserved sulfatase family of enzymes that catalyze the hydrolysis of O- and N-sulfate esters from a variety of substrates. The human Iduronate 2-Sulfatase/IDS consists of a signal peptide, a propeptide, and a mature chain that may be further processed into two chains. Among the identified 18 human sulfatases, Iduronate 2-Sulfatase/IDS is required for the lysosomal degradation of the glycosaminoglycans (GAG), heparan sulfate, and dermatan sulfate. Multiple mutations in this X-chromosome localized gene result in Iduronate 2-Sulfatase/IDS enzymatic deficiency and lead to the sex-linked Mucopolysaccharidosis Type II (MPS II ), also known as Hunter Syndrome characterized by the lysosomal accumulation of the GAG and their excretion in urine. MPS II has a wide spectrum of clinical manifestations ranging from mild to severe due to the level of Iduronate 2-Sulfatase/IDS enzyme. Retroviral-mediated Iduronate 2-Sulfatase/IDS gene transfer into lymphoid cells would be a promising gene therapeutic strategy.
存储条件Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months
关键字MPS-2 | MPS 2
SIDS;MPS2;iduronate 2-sulfatase;IDS;TargetMol

公司简介


成立日期 (14年)
注册资本 589.8595万人民币
员工人数 100-500人
年营业额 ￥ 1亿以上
经营模式 贸易,工厂,试剂,定制,服务
主营行业 天然产物,生物化工,化学试剂,生物技术服务

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