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网站主页 DDOST, HUMAN, 重组蛋白 DDOST, Human, 重组蛋白
  • DDOST, Human, 重组蛋白|TMPY-02050|TargetMol

DDOST, Human, 重组蛋白|TMPY-02050|TargetMol

DDOST Protein, Human, Recombinant
￥5100 100μg 起订
上海 更新日期：2026-05-08

TargetMol 中国（陶术生物）

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产品详情:

中文名称：
DDOST, Human, 重组蛋白
英文名称：
DDOST Protein, Human, Recombinant
品牌：
TargetMol
产地：
美国
保存条件：
Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months
产品类别：
抑制剂
种属：
Human
表达系统：
E. coli
蛋白长度：
A DNA sequence encoding the human DDOST (P39656-1) extracellular domain (Ser 43-Pro 427) was expressed and purified, with additional two amino acids (Gly & Pro) at the N-terminus. Predicted N terminal: Gly
标签：
Tag Free
货号：
T011|TMPY-02050

Product Introduction

Bioactivity

名称DDOST Protein, Human, Recombinant
描述The enzyme oligosaccharyltransferase (dolichyl-diphosphooligosaccharide-protein glycosyltransferase) (DDOST), or 48-kDa subunit (OST48) is one of the catalytic subunits in this complex, exerts a typical type I membrane topology, containing a large luminal domain, a hydrophobic transmembrane domain and a short cytosolic peptide tail. DDOST/OST48 catalyzes the transfer of a high-mannose oligosaccharide (GlcNac2Man9Glc3) from a dolichol-linked oligosaccharide donor (dolichol-P-GlcNac2Man9Glc3) onto the asparagine acceptor site within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains across the membrane of the endoplasmic reticulum. The mammalian oligosaccharyltransferase (OST) is an oligomeric complex composed of three type I transmembrane proteins of the endoplasmic reticulum: ribophorin I (RI), ribophorin II (RII), and OST48. OST48 is not a glycoprotein and is not recognized by antibodies to either ribophorin. Like ribophorins I and II, OST48 was found to be an integral membrane protein, with the majority of the polypeptide located within the lumen of the endoplasmic reticulum (ER). OST48 does not show significant amino acid sequence homology to either ribophorin I or II. It had been found that only the luminal domain of RI contains ER retention information. The dilysine motif in OST48 functions as an ER localization motif because OST48 in which the two lysine residues are replaced by serine (OST48ss) is no longer retained in the ER and is found instead also at the plasma membrane.
存储条件Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months
关键字WBP-1 | WBP 1 | OST-48 | OST 48 | non-catalytic | AGER-1 | AGER 1
WBP1;OST48;OST;OKSWcl45;dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic);CDG1R;AGER1;TargetMol

公司简介


成立日期 (14年)
注册资本 589.8595万人民币
员工人数 100-500人
年营业额 ￥ 1亿以上
经营模式 贸易,工厂,试剂,定制,服务
主营行业 天然产物,生物化工,化学试剂,生物技术服务

DDOST, Human, 重组蛋白相关厂家报价

  • 重组蛋白
  • 重组蛋白
  • 爱必信（上海）生物科技有限公司 VIP
  • 2026-06-12
  • ￥1500
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