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网站主页 COAGULATION FACTOR XIII B/F13B , HUMAN, 重组蛋白 (HIS) Coagulation factor XIII B/F13B , Human, 重组蛋白 (His)
  • Coagulation factor XIII B/F13B , Human, 重组蛋白 (His)|TMPY-02185|TargetMol

Coagulation factor XIII B/F13B , Human, 重组蛋白 (His)|TMPY-02185|TargetMol

Coagulation factor XIII B/F13B Protein, Human, Recombinant (His)
1890 20μg 起订
上海 更新日期:2026-05-08

TargetMol 中国(陶术生物)

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产品详情:

中文名称:
Coagulation factor XIII B/F13B , Human, 重组蛋白 (His)
英文名称:
Coagulation factor XIII B/F13B Protein, Human, Recombinant (His)
品牌:
TargetMol
产地:
美国
保存条件:
Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months
产品类别:
抑制剂
种属:
Human
表达系统:
HEK293 Cells
蛋白长度:
A DNA sequence encoding the human F13B (P05160) (Met 1-Thr 661) was expressed, fused with a polyhistidine tag at the C-terminus. Predicted N terminal: Glu 21
标签:
C-His
货号:
T011|TMPY-02185

Product Introduction

Bioactivity

名称Coagulation factor XIII B/F13B Protein, Human, Recombinant (His)
描述Coagulation factor XIII B chain, also known as Fibrin-stabilizing factor B subunit, Protein-glutamine gamma-glutamyltransferase B chain, Transglutaminase B chain and F13B, is a secreted protein which contains 1 Sushi ( CCP / SCR ) domains. Coagulation factor XIII is the last zymogen to become activated in the blood coagulation cascade. Plasma factor XIII is a heterotetramer composed of 2 A subunits and 2 B subunits. The A subunits have catalytic function, and the B subunits do not have enzymatic activity and may serve as a plasma carrier molecules. Platelet factor XIII is composed of just 2 A subunits, which are identical to those of plasma origin. The B chain of factor XIII is not catalytically active, but is thought to stabilize the A subunits and regulate the rate of transglutaminase formation by thrombin. Factor XIII acts as a transglutaminase to catalyze the formation of gamma-glutamyl-epsilon-lysine crosslinking between fibrin molecules, thus stabilizing the fibrin clot. Factor XIII deficiency is classified into two categories: type I deficiency, characterized by the lack of both the A and B subunits; and type II deficiency, characterized by the lack of the A subunit alone. These defects can result in a lifelong bleeding tendency, defective wound healing, and habitual abortion. Defects in F13B are the cause of factor XIII subunit B deficiency ( FA13BD ) which is an autosomal recessive disorder characterized by a life-long bleeding tendency, impaired wound healing and spontaneous abortion in affected women.
存储条件Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months
FXIIIB;coagulation factor XIII, B polypeptide;Coagulation factor XIII;Coagulation factor 13;TargetMol

公司简介


成立日期 (14年)
注册资本 589.8595万人民币
员工人数 100-500人
年营业额 ¥ 1亿以上
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