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  • PCNA, Human, 重组蛋白 (His)|TMPY-02543|TargetMol

PCNA, Human, 重组蛋白 (His)|TMPY-02543|TargetMol

PCNA Protein, Human, Recombinant (His)
4460 100μg 起订
上海 更新日期:2026-05-08

TargetMol 中国(陶术生物)

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联系人:邵经理
电话:400-821-0310拨打
手机:15002144251 拨打
邮箱:xuexiang.shao@tsbiochem.com

产品详情:

中文名称:
PCNA, Human, 重组蛋白 (His)
英文名称:
PCNA Protein, Human, Recombinant (His)
品牌:
TargetMol
产地:
美国
保存条件:
Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months
纯度规格:
93.70%
产品类别:
抑制剂
种属:
Human
表达系统:
Baculovirus Insect Cells
蛋白长度:
A DNA sequence encoding the mature form of human PCNA (P12004) (Met 1-Ser 261) was expressed, with a polyhistidine tag at the N-terminus. Predicted N terminal: Met
标签:
N-His
货号:
T011|TMPY-02543

Product Introduction

Bioactivity

名称PCNA Protein, Human, Recombinant (His)
描述Proliferating Cell Nuclear Antigen (PCNA) is a protein only expressed in normal proliferate cells and cancer cells. It is central to both DNA replication and repair. One of the well-established functions for PCNA is its role as the processivity factor for DNA polymerase delta and epsilon. PCNA tethers the polymerase catalytic unit to the DNA template for rapid and processive DNA synthesis. Two forms of PCNA exist in cells: (i) a detergent-insoluble trimeric form stably associated with the replicating forks during S phase and (ii) a soluble form in quiescent cells in G1 and G2 phases. PCNA forms a toroidal trimer in S phase with replication factor-C (RF-C) and DNA in an ATP-dependent manner and enables the loading of DNA polymerase delta and epsilon onto the complex. The close association of PCNA with kinase complexes involved in cell cycle machinery indicates that PCNA has a regulatory role in cell cycle progression. PCNA also participates in the processing of branched intermediates that arise during the lagging strand DNA synthesis.
存储条件Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months
关键字ATLD-2 | ATLD 2
proliferating cell nuclear antigen;ATLD2;TargetMol

公司简介


成立日期 (14年)
注册资本 589.8595万人民币
员工人数 100-500人
年营业额 ¥ 1亿以上
经营模式 贸易,工厂,试剂,定制,服务
主营行业 天然产物,生物化工,化学试剂,生物技术服务

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