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网站主页 Annexin V/ANXA5 重组蛋白, FITC conjugated Annexin V/ANXA5 重组蛋白, FITC conjugated
  • Annexin V/ANXA5 重组蛋白, FITC conjugated|TMPY-00540|TargetMol

Annexin V/ANXA5 重组蛋白, FITC conjugated|TMPY-00540|TargetMol

Annexin V/ANXA5 Protein, FITC conjugated
￥2230 200μg 起订
上海 更新日期：2026-05-08

TargetMol 中国（陶术生物）

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联系人：邵经理
电话：400-821-0310拨打
手机：15002144251 拨打
邮箱：xuexiang.shao@tsbiochem.com

产品详情:

中文名称：
Annexin V/ANXA5 重组蛋白, FITC conjugated
英文名称：
Annexin V/ANXA5 Protein, FITC conjugated
品牌：
TargetMol
产地：
美国
保存条件：
Keep away from direct sunlight Store at 4°C
产品类别：
抑制剂
货号：
TMPY-00540

Product Introduction

Bioactivity

名称Annexin V/ANXA5 Protein, FITC conjugated
描述The placental anticoagulant protein Annexin A5 (ANXA5) is a multifunctional protein that is highly expressed on the apical surfaces of syncytiotrophoblasts, and plays an important role in haemostatic regulations, maintaining blood fluidity of the placenta. Annexin A5 (ANXA5) is a protein abundantly expressed in normal placenta where it contributes to the healthy outcome of a pregnancy. Lower ANXA5 levels have been observed in M2/ANXA5 haplotype carrying chorion. The association found between the maternal carriage of the M2/ANXA5 haplotype and an elevated risk of IUGR and/or PE supports the hypothesis that carrier status of this haplotype and the consequently reduced placental ANXA5 expression might be responsible, at least partially, for the onset of these gestational vascular complications. ANXA5 could be used as a biomarker for the early detection of PE and for the prediction of its severity. ANXA5 as an embryonic anticoagulant that appears deficient in contiguous specter of thrombophilia-related pregnancy complications culminating more frequently in miscarriage in a maternal M2 carrier background. As a potential indicator for malignancy and lymphatic metastasis, ANXA5 overexpression increases in vitro migration and invasion of Hca-P cell, promotes in vivo malignancy, LNM rate and level of Hca-P-transplanted mice. Hereditary thrombophilias can impair vascular placental functions and predispose to the birth of small-for-gestational age (SGA) babies. The placental anticoagulant protein annexin A5 (ANXA5) may contribute to this process. A functional haplotype (M2) within the ANXA5 gene is associated with fetal loss and venous thrombosis.
存储条件Keep away from direct sunlight Store at 4°C
br
annexin A5|TargetMol

公司简介


成立日期 (14年)
注册资本 589.8595万人民币
员工人数 100-500人
年营业额 ￥ 1亿以上
经营模式 贸易,工厂,试剂,定制,服务
主营行业 天然产物,生物化工,化学试剂,生物技术服务

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