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网站主页 COX-2, HUMAN, 重组蛋白 (HIS) COX-2, Human, 重组蛋白 (His)
  • COX-2, Human, 重组蛋白 (His)|TMPY-01736|TargetMol

COX-2, Human, 重组蛋白 (His)|TMPY-01736|TargetMol

COX-2 Protein, Human, Recombinant (His)
6530 100μg 起订
上海 更新日期:2026-05-08

TargetMol 中国(陶术生物)

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电话:400-821-0310拨打
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邮箱:xuexiang.shao@tsbiochem.com

产品详情:

中文名称:
COX-2, Human, 重组蛋白 (His)
英文名称:
COX-2 Protein, Human, Recombinant (His)
品牌:
TargetMol
产地:
美国
保存条件:
Store at low temperature Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months
纯度规格:
92.10%
产品类别:
抑制剂
种属:
Human
表达系统:
Baculovirus Insect Cells
蛋白长度:
A DNA sequence encoding the human PTGS2 (NP_000954.1) (Met 1-Leu 604) was fused with a polyhistidine tag at the C-terminus. Predicted N terminal: Ala 18
标签:
C-His
货号:
T011|TMPY-01736

Product Introduction

Bioactivity

名称COX-2 Protein, Human, Recombinant (His)
描述PTGS2, also known as COX-2, is s component of Prostaglandin-endoperoxide synthase (PTGS). PTGS, also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. PTGS2 is overexpressed in many cancers. The overexpression of PTGS2 along with increased angiogenesis and GLUT-1 expression is significantly associated with gallbladder carcinomas. Furthermore the product of COX-2, PGH2 is converted by prostaglandin E2 synthase into PGE2, which in turn can stimulate cancer progression. Consequently inhibiting COX-2 may have benefit in the prevention and treatment of these types of cancer. PTGS2 is regulated by specific stimulatory events, suggesting that it is responsible for the prostanoid biosynthesis involved in inflammation and mitogenesis. It mediates the formation of prostaglandins from arachidonate and may have a role as a major mediator of inflammation and/or a role for prostanoid signaling in activity-dependent plasticity.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy
存储条件Store at low temperature Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months
关键字PHS2 | PHS 2 | PGHS2 | PGHS 2 | COX 2
prostaglandin-endoperoxide synthase 2;PHS-2;PGHS-2;PGG/HS;hCox-2;GRIPGHS;COX-2;COX2;TargetMol

公司简介


成立日期 (14年)
注册资本 589.8595万人民币
员工人数 100-500人
年营业额 ¥ 1亿以上
经营模式 贸易,工厂,试剂,定制,服务
主营行业 天然产物,生物化工,化学试剂,生物技术服务

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