帕西瑞肽 新品

Product Name：Pasireotide

CAS No.：396091-73-9；396091-76-2（Hac）；1421446-02-7(diaspartate)

Synonyms：帕西瑞肽;SOM230

Catalog No.：218P051

Description：Pasireotide是一种结构为环六肽的生长抑素类似物，序列中含有4个非天然氨基酸，作为药物主要成分的Pasireotide适用于未进行垂体手术或手术未治愈的库欣氏病成年患者的治疗。同Octreotide相比，Pasireotide有更长的半衰期、能与更多受体结合，抑制胰腺分泌，抑制肠道蛋白水解酶的活性，通过这些机制来降低胰腺术后并发症。

Pasireotide is a growth hormone analogue with a cyclic hexapeptide structure, containing four non natural amino acids in its sequence. As the main component of the drug, Pasireotide is suitable for the treatment of adult patients with Cushing's disease who have not undergone pituitary surgery or have not been cured by surgery. Compared with Octreotide, Pasireotide has a longer half-life, can bind to more receptors, inhibit pancreatic secretion, and suppress the activity of intestinal proteolytic enzymes, thereby reducing pancreatic postoperative complications through these mechanisms.

Purity (HPLC) ≥98.0%

Single impurity≤2%

Peptide content≥75.0%

Amino Acid Composition≤±15%

Bacterial Endotoxins≤50EU/mg

Solubility：H2O/DMSO

Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.

Storage:Cool dry place( Store at -20°C, away from the light)

Remark:For Research Use Only. Not for human use.