Pannexin-1（Panx1）模拟抑制肽，10Panx，955091-53-9，杭州固拓生物多肽物美价廉 新品

Product Name：10Panx

Synonyms：Pannexin-1（Panx1）模拟抑制肽

CAS No.：955091-53-9

Catalog No.：GT-XL0214

Brand：Go Top peptide（杭州固拓）

Description：10Panx是一种模拟Pannexin-1（Panx1）第二胞外环序列的抑制性肽段，能够阻断Pannexin-1间隙连接/半通道。它可以抑制P2X7受体介导的染料摄取、ATP介导的IL-1β释放及caspase-1激活，还可阻断NMDA受体次级电流（I₂ₙd），常用于神经病变、炎症和细胞信号转导研究。

10Panx is an inhibitory peptide segment that mimics the second extracellular loop sequence of Pannexin-1 (Panx1) and can block Pannexin-1 gap junctions/hemichannels. It can inhibit P2X7 receptor-mediated dye uptake, ATP-mediated IL-1β release, and caspase-1 activation, and can also block NMDA receptor secondary currents (I₂ₙd). It is commonly used in research on neuropathies, inflammation, and cell signal transduction.

Purity (HPLC) ≥98.0%

Single impurity≤2%

Peptide content≥75.0%

Amino Acid Composition≤±15%

Bacterial Endotoxins≤50EU/mg

Solubility：H2O/DMSO

Vacuum-packedwith aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.

Storage:Cool dry place( Store at -20°C, away from the light)

Remark:For Research Use Only. Not for human use.

Sequence(1-letter code)	WRQAAFVDSY
Sequence(3-letter code)	H-Trp-Arg-Gln-Ala-Ala-Phe-Val-Asp-Ser-Tyr-OH
Peptide Structure
Molecular Formula	C58H79N15O16
Molecular Weight	1242.36

申明：产品仅供科研使用，不得用于人体。

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