RMC-6291 新品

CAS号:2641998-63-0

英文名:RMC6291

英文别名:RMC6291;elironrasib;RMC6291/Elironrasib;Elironrasib(RMC-6291);2-(1-{1-[4-(dimethylamino)-4-methylpent-2-ynoyl]-4-fluoropiperidin-4-yl}-N-methylformamido)-N-{22-ethyl-21-[2-(1-methoxyethyl)pyridin-3-yl]-18,18-dimethyl-9,15-dioxo-5,16-dioxa-2,10,22,28-tetraazapentacyclo[18.5.2.12,?.11?,1?.023,2?]nonacosa-1(25),20,23,26-tetraen-8-yl}-3-methylbutanamide_chiral;(3S)-N1-[N-[[1-[4-(Dimethylamino)-4-methyl-1-oxo-2-pentyn-1-yl]-4-fluoro-4-piperidinyl]carbonyl]-N-methyl-L-valyl-3-[4-[(2R)-1-ethyl-3-(3-hydroxy-2,2-dimethylpropyl)-2-[2-[(1S)-1-methoxyethyl]-3-pyridinyl]-1H-indol-5-yl]-2-morpholinyl]-L-alanyl]hexahydro-3-pyridazinecarboxylicacid(3→2)-lactone;3-Pyridazinecarboxylicacid,N1-[N-[[1-[4-(dimethylamino)-4-methyl-1-oxo-2-pentyn-1-yl]-4-fluoro-4-piperidinyl]carbonyl]-N-methyl-L-valyl-3-[4-[(2R)-1-ethyl-3-(3-hydroxy-2,2-dimethylpropyl)-2-[2-[(1S)-1-methoxyethyl]-3-pyridinyl]-1H-indol-5-yl]-2-morpholinyl]-L-alanyl]hexahydro-,(3→2)-lactone,(3S)…

中文名:RMC-6291中文别名:化合物RMC-6291;KRASG12C抑制剂;(3S)-N1-[N-[[1-[4-(二甲基氨基)-4-甲基-1-氧代-2-戊炔-1-基]-4-氟-4-哌啶基]羰基]-N-甲基-L-缬氨酰-3-[4-[(2R)-1-乙基-3-(3-羟基-2,2-二甲基丙基)-2-[2-[(1S)-1-甲氧基乙基]-3-吡啶基]-1H-吲哚-5-基]-2-吗啉基]-L-丙氨酰]六氢-3-哒嗪羧酸(3→2)-内酯;(3S)-N1-[N-[[1-[4-(二甲基氨基)-4-甲基-1-氧代-2-戊炔-1-基]-4-氟-4-哌啶基]羰基]-N-甲基-L-缬氨酰基-3-[4-[(2R)-1-乙基-3-(3-羟基-2,2-二甲基丙基)-2-[2-[(1S)-1-甲氧基乙基]-3-吡啶基]-1H-吲哚-5-基]-2-吗啉基]-L-丙氨酰基]六氢-3-哒嗪甲酸(3→2)-内酯

CBNumber:CB113267341

分子式:C55H78FN9O8

分子量:1012.28