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网站主页 PADI4, HUMAN, 重组蛋白 (HIS) PADI4, Human, 重组蛋白 (His)
  • PADI4, Human, 重组蛋白 (His)|TMPY-00021|TargetMol

PADI4, Human, 重组蛋白 (His)|TMPY-00021|TargetMol

PADI4 Protein, Human, Recombinant (His)
￥2230 20μg 起订
上海 更新日期：2026-05-08

TargetMol 中国（陶术生物）

VIP1年
联系人：邵经理
电话：400-821-0310拨打
手机：15002144251 拨打
邮箱：xuexiang.shao@tsbiochem.com

产品详情:

中文名称：
PADI4, Human, 重组蛋白 (His)
英文名称：
PADI4 Protein, Human, Recombinant (His)
品牌：
TargetMol
产地：
美国
保存条件：
Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months
纯度规格：
91.90%
产品类别：
抑制剂
种属：
Human
表达系统：
Baculovirus Insect Cells
蛋白长度：
A DNA sequence encoding the human PADI4 (Q9UM07) (Met1-Pro663) was expressed with a polyhistidine tag at the N-terminus. Predicted N terminal: Met
标签：
N-His
货号：
T011|TMPY-00021

Product Introduction

Bioactivity

名称PADI4 Protein, Human, Recombinant (His)
描述Protein-arginine deiminase type-4, also known as HL-6 PAD, Peptidylarginine deiminase IV, Protein-arginine deiminase type I V and PADI4, is a cytoplasm and nucleus protein that belongs to the protein arginine deiminase family. PADI4 is expressed in CD34+stem cells in normal tissues, and many more CD34+ cells expressing PADI4 are present in tumour tissues. PADI4 post-translationally converts peptidylarginine to citrulline, a process called citrullination. Studies have demonstrated the high expression of PADI4 in various malignant tumor tissues. PADI4 is also expressed at high levels in the blood of patients with some malignant tumors. Citrullination of histone, cytokeratin, antithrombin and fibronectin have been confirmed to be involved in abnormal apoptosis, high coagulation, and disordered cell proliferation and differentiation, all of which are main features of malignant tumors. PADI4 may play an important role in tumorigenesis. Genetic variations in PADI4 are a cause of susceptibility to rheumatoid arthritis (RA). It is a systemic inflammatory disease with autoimmune features and a complex genetic component. It primarily affects the joints and is characterized by inflammatory changes in the synovial membranes and articular structures, widespread fibrinoid degeneration of the collagen fibers in mesenchymal tissues, and by atrophy and rarefaction of bony structures.
存储条件Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months
关键字PDI-5 | PDI-4 | PDI 5 | PDI 4 | PADI-5 | PADI 5 | PAD-4 | PAD 4
peptidyl arginine deiminase, type IV;PDI5;PDI4;PADI5;PAD4;PAD;TargetMol

公司简介


成立日期 (14年)
注册资本 589.8595万人民币
员工人数 100-500人
年营业额 ￥ 1亿以上
经营模式 贸易,工厂,试剂,定制,服务
主营行业 天然产物,生物化工,化学试剂,生物技术服务

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