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网站主页 BMP5, HUMAN, 重组蛋白 (HFC) BMP5, Human, 重组蛋白 (hFc)
  • BMP5, Human, 重组蛋白 (hFc)|TMPY-00681|TargetMol

BMP5, Human, 重组蛋白 (hFc)|TMPY-00681|TargetMol

BMP-5 Protein, Human, Recombinant (hFc)
￥1350 20μg 起订
上海 更新日期：2026-05-08

TargetMol 中国（陶术生物）

VIP1年
联系人：邵经理
电话：400-821-0310拨打
手机：15002144251 拨打
邮箱：xuexiang.shao@tsbiochem.com

产品详情:

中文名称：
BMP5, Human, 重组蛋白 (hFc)
英文名称：
BMP-5 Protein, Human, Recombinant (hFc)
品牌：
TargetMol
产地：
美国
保存条件：
Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months
产品类别：
抑制剂
种属：
Human
表达系统：
HEK293 Cells
蛋白长度：
A DNA sequence encoding the carboxy-terminal domain (Gln 324-His 454) (the mature chain) of human BMP5 (NP_066551.1) was expressed with the fused Fc region of human IgG1 at the N-terminus. Predicted N terminal: Glu 20
标签：
N-hFc
货号：
T011|TMPY-00681

Product Introduction

Bioactivity

名称BMP-5 Protein, Human, Recombinant (hFc)
描述Bone Morphogenetic Protein 5 (BMP-5) is a member of the structurally and functionally related bone morphogenetic proteins (BMPs) which constitute a novel subfamily of the transforming growth factor β (TGF-β) superfamily. In agreement with a possible role in the control of cell death, BMP-5 exhibited a regulated pattern of expression in the interdigital tissue. Transcripts of BMP-5 and BMP-5 protein were abundant within the cytoplasm of the fragmenting apoptotic interdigital cells in a way suggesting that delivery of BMPs into the tissue is potentiated during apoptosis. Gain-of-function experiments demonstrated that BMP-5 has the same effect as other interdigital BMPs inducing apoptosis in the undifferentiated mesoderm and growth in the prechondrogenic mesenchyme. BMP-5 is a member of the 60A subgroup of BMPs, other members of which have been shown to stimulate dendritic growth in central and peripheral neurons. The signaling pathway that mediates the dendrite-promoting activity of BMP-5 may involve binding to BMPR-IA and activation of Smad-1, and relative levels of BMP antagonists such as noggin and follistatin may modulate BMP-5 signaling. Since BMP-5 is expressed at relatively high levels not only in the developing but also the adult nervous system, these findings suggest the possibility that BMP-5 regulates dendritic morphology not only in the developing but also the adult nervous system. BMP-5 may play important roles not only in myocardial differentiation but also in the formation and maintenance of endocardial cushion tissue. Additionally, a high expression level of BMP-5 has been detected in certain tumors of mesenchymal origin.
存储条件Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months
bone morphogenetic protein 5;TargetMol

公司简介


成立日期 (14年)
注册资本 589.8595万人民币
员工人数 100-500人
年营业额 ￥ 1亿以上
经营模式 贸易,工厂,试剂,定制,服务
主营行业 天然产物,生物化工,化学试剂,生物技术服务

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