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  • HSC70, Human, 重组蛋白 (His)|TMPY-02217|TargetMol

HSC70, Human, 重组蛋白 (His)|TMPY-02217|TargetMol

HSC70 Protein, Human, Recombinant (His)
697 10μg 起订
上海 更新日期:2026-05-08

TargetMol 中国(陶术生物)

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产品详情:

中文名称:
HSC70, Human, 重组蛋白 (His)
英文名称:
HSC70 Protein, Human, Recombinant (His)
品牌:
TargetMol
产地:
美国
保存条件:
Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months
产品类别:
抑制剂
种属:
Human
表达系统:
E. coli
蛋白长度:
A DNA sequence encoding the human HSPA8 (P11142-1) (Met 1-Asp 646) was expressed, with a polyhistide tag at the N-terminus. Predicted N terminal: Met
标签:
N-His
货号:
T011|TMPY-02217

Product Introduction

Bioactivity

名称HSC70 Protein, Human, Recombinant (His)
描述HSPA8, also known as HSC70, is a member of the heat shock protein family due to homology with other heat shock proteins. The heat shock protein 70 family is comprised of both heat-inducible and constitutively expressed members. The latter are called heat-shock cognate proteins. HSPA8 belongs to the heat-shock cognate subgroup. Members of the human heat-shock protein multigene family have several highly conserved proteins with structural and functional properties in common but vary in the extent of their inducibility in response to metabolic stress. HSPA8 is constitutively expressed and performs functions related to normal cellular processes. This protein binds to nascent polypeptides to facilitate correct protein folding. It also functions as an ATPase in the disassembly of clathrin-coated vesicles during the transport of membrane components through the cell. Two alternatively spliced variants have been characterized to date. HSPA8 acts as a repressor of transcriptional activation. It inhibits the transcriptional coactivator activity of CITED1 on Smad-mediated transcription. Isoform 2 may function as an endogenous inhibitory regulator of HSC70 by competing with the co-chaperones. It also is an ATPase that works with Auxilin to remove clathrin-coated vesicles. In neurons, synaptojanin is also an important protein involved in vesicle uncoating.
存储条件Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months
关键字NIP-71 | NIP 71 | LAP 1 | HSPA-10 | HSPA 10 | HSP-73 | HSP-71 | HSP 73 | HSP 71 | HSC-71 | HSC-70 | HSC-54 | HSC 71 | HSC 70 | HSC 54 | HEL33 | HEL 33
NIP71;LAP-1;LAP1;HSPA10;HSP73;HSP71;HSC71;HSC70;HSC54;HEL-S-72p;HEL-33;heat shock 70kDa protein 8;TargetMol

公司简介


成立日期 (14年)
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