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网站主页 Lyn A, Human, 重组蛋白 (GST) Lyn A, Human, 重组蛋白 (GST)
  • Lyn A, Human, 重组蛋白 (GST)|TMPY-04391|TargetMol

Lyn A, Human, 重组蛋白 (GST)|TMPY-04391|TargetMol

Lyn A Protein, Human, Recombinant (GST)
￥585 5μg 起订
上海 更新日期：2026-05-08

TargetMol 中国（陶术生物）

VIP1年
联系人：邵经理
电话：400-821-0310拨打
手机：15002144251 拨打
邮箱：xuexiang.shao@tsbiochem.com

产品详情:

中文名称：
Lyn A, Human, 重组蛋白 (GST)
英文名称：
Lyn A Protein, Human, Recombinant (GST)
品牌：
TargetMol
产地：
美国
保存条件：
Store at low temperature Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months
产品类别：
抑制剂
种属：
Human
表达系统：
Baculovirus Insect Cells
蛋白长度：
A DNA sequence encoding the human LYN isoform a (NP_002341.1) (Met 1-Pro 512) was fused with the GST tag at the N-terminus. Predicted N terminal: Met
标签：
N-GST
货号：
T011|TMPY-04391

Product Introduction

Bioactivity

名称Lyn A Protein, Human, Recombinant (GST)
描述Tyrosine-protein kinase Lyn is a member of the Src family of protein tyrosine kinases, which is mainly expressed in hematopoietic cells, in neural tissues liver, and adipose tissue. Tyrosine-protein kinase Lyn has many functions. Lyn kinase may downregulate the expression of stem cell growth factor receptor (KIT). Lyn kinase Acts as an effector of EpoR (erythropoietin receptor) in controlling KIT expression and may play a central role in erythroid differentiation during the switch between proliferation and maturation. Lyn kinase also acts as a positive regulator of cell movement while negatively regulating adhesion to stromal cells by inhibiting the ICAM-1-binding activity of beta-2 integrins. Lyn kinase relays suppressing signals from the chemokine receptor CXCR4 to beta-2 integrin LFA-1 in hematopoietic precursors. This kinase is involved in the induction of stress-activated protein kinase (SAPK), but not ERK or p38 MAPK, in response to genotoxic agents. In a word, Lyn kinase functions primarily as a negative regulator, but can also function as an activator, depending on the context. Tyrosine-protein kinase Lyn is Required for the initiation of the B-cell response, but also its down-regulation and termination. It also plays an important role in the regulation of B-cell differentiation, proliferation, survival, and apoptosis, and is important for immune self-tolerance. It has been reported that Lyn kinase plays a role in the inflammatory response to bacterial lipopolysaccharide. Lyn kinase Mediates the responses to cytokines and growth factors in hematopoietic progenitors, platelets, erythrocytes, and in mature myeloid cells, such as dendritic cells, neutrophils, and eosinophils.
存储条件Store at low temperature Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months
关键字JTK-8 | JTK 8
p56Lyn;p53Lyn;LYN proto-oncogene, Src family tyrosine kinase;JTK8;TargetMol

公司简介


成立日期 (14年)
注册资本 589.8595万人民币
员工人数 100-500人
年营业额 ￥ 1亿以上
经营模式 贸易,工厂,试剂,定制,服务
主营行业 天然产物,生物化工,化学试剂,生物技术服务

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