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网站主页 PDK1, HUMAN, 重组蛋白 (HIS) PDK1, Human, 重组蛋白 (His)
  • PDK1, Human, 重组蛋白 (His)|TMPY-04568|TargetMol

PDK1, Human, 重组蛋白 (His)|TMPY-04568|TargetMol

PDK1 Protein, Human, Recombinant (His)
3820 50μg 起订
上海 更新日期:2026-05-08

TargetMol 中国(陶术生物)

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电话:400-821-0310拨打
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产品详情:

中文名称:
PDK1, Human, 重组蛋白 (His)
英文名称:
PDK1 Protein, Human, Recombinant (His)
品牌:
TargetMol
产地:
美国
保存条件:
Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months
产品类别:
抑制剂
种属:
Human
表达系统:
Baculovirus Insect Cells
蛋白长度:
A DNA sequence encoding the mature form of human PDK1 (NP_002601.1) (Ser 29-Ala 436) was expressed, with a polyhistidine tag at the N-terminus. Predicted N terminal: His
标签:
N-His
货号:
T011|TMPY-04568

Product Introduction

Bioactivity

名称PDK1 Protein, Human, Recombinant (His)
描述Pyruvate dehydrogenase kinase, isozyme 1, also known as [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 1, mitochondrial and PDK1, is a member of the PDK / BCKDK protein kinase family. PDK-1 is expressed predominantly in the heart. It contains one histidine kinase domain. Pyruvate dehydrogenase kinase (PDK) isoforms are molecular switches that downregulate the pyruvate dehydrogenase complex (PDC) by reversible phosphorylation in mitochondria. An inhibitory effect of lipoic acid on PDKs would result in less phosphorylation of E1 and hence increased PDC activity. At least two isoenzymic forms of pyruvate dehydrogenase kinase ( PDK-1 and PDK-2 ) may be involved in the regulation of enzymatic activity of mammalian pyruvate dehydrogenase complex by phosphorylation. PDK-3 appears to have the highest specific activity among the three isoenzymes. PDK-1 inhibits the mitochondrial pyruvate dehydrogenase complex by phosphorylation of the E1 alpha subunit, thus contributing to the regulation of glucose metabolism.
存储条件Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months
关键字PDHK-1 | PDHK 1
pyruvate dehydrogenase kinase, isozyme 1;PDHK1;TargetMol

公司简介


成立日期 (14年)
注册资本 589.8595万人民币
员工人数 100-500人
年营业额 ¥ 1亿以上
经营模式 贸易,工厂,试剂,定制,服务
主营行业 天然产物,生物化工,化学试剂,生物技术服务

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