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网站主页 PAH, HUMAN, 重组蛋白 (415 ASN/ASP, HIS) PAH, Human, 重组蛋白 (415 Asn/Asp, His)
  • PAH, Human, 重组蛋白 (415 Asn/Asp, His)|TMPY-02707|TargetMol

PAH, Human, 重组蛋白 (415 Asn/Asp, His)|TMPY-02707|TargetMol

PAH Protein, Human, Recombinant (415 Asn/Asp, His)
1890 20μg 起订
上海 更新日期:2026-05-08

TargetMol 中国(陶术生物)

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产品详情:

中文名称:
PAH, Human, 重组蛋白 (415 Asn/Asp, His)
英文名称:
PAH Protein, Human, Recombinant (415 Asn/Asp, His)
品牌:
TargetMol
产地:
美国
保存条件:
Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months
纯度规格:
83.60%
产品类别:
抑制剂
种属:
Human
表达系统:
Baculovirus Insect Cells
蛋白长度:
A DNA sequence encoding the human PAH (P00439) (Met 1-Lys 452) (415 Asn/Asp) was expressed, with a polyhistidine tag at the N-terminus. Predicted N terminal: Met
标签:
N-His
货号:
T011|TMPY-02707

Product Introduction

Bioactivity

名称PAH Protein, Human, Recombinant (415 Asn/Asp, His)
描述PAH (phenylalanine hydroxylase), also known as PH, belongs to the biopterin-dependent aromatic amino acid hydroxylase family. It contains 1 ACT domain, N-terminal region of PAH is thought to contain allosteric binding sites for phenylalanine and to constitute an "inhibitory" domain that regulates the activity of a catalytic domain in the C-terminal portion of the molecule. In humans, PAH is expressed both in the liver and the kidney, and there is some indication that it may be differentially regulated in these tissues. PAH catalyzes the hydroxylation of the aromatic side-chain of phenylalanine to generate tyrosine. It is one of three members of the pterin-dependent amino acid hydroxylases, a class of monooxygenase that uses tetrahydrobiopterin and a non-heme iron for catalysis. Defects in PAH are the cause of phenylketonuria (PKU). PKU is an autosomal recessive inborn error of phenylalanine metabolism, due to severe phenylalanine hydroxylase deficiency. It is characterized by blood concentrations of phenylalanine persistently above 1200 mumol.
存储条件Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months
关键字PKU-1 | PKU 1
PKU1;PKU;phenylalanine hydroxylase;PH;TargetMol

公司简介


成立日期 (14年)
注册资本 589.8595万人民币
员工人数 100-500人
年营业额 ¥ 1亿以上
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