抗肿瘤特性细胞穿透肽CIGB-552/1630763-23-3/CIGB-552 新品

Product Name：CIGB-552

CAS No.：1630763-23-3

Synonyms：抗肿瘤特性细胞穿透肽CIGB-552

Catalog No.：220P335

Brand：Typeptide Biotech（肽研生物）

Description：CIGB-552 是一种具有抗肿瘤特性的细胞穿透肽，是由20个氨基酸组成的多肽，序列中含有D型氨基酸，在 H460 细胞中的 IC50 为 23 μM。CIGB-552 可以增加 COMMD1 蛋白的水平。CIGB-552 显著抑制 NF-κB 信号通路。CIGB-552 可以促进肿瘤细胞的凋亡 (apoptosis)。CIGB-552 可以诱导肿瘤细胞中活性氧 (ROS) 的积累。CIGB-552 具有抗炎和抗血管生成作用。CIGB-552 可用于肺癌和结肠癌的研究。

CIGB-552 is a cell penetrating peptide with anti-tumor properties, consisting of 20 amino acids and containing D-type amino acids in its sequence. Its IC50 in H460 cells is 23 μ M. CIGB-552 can increase the level of COMMD1 protein. CIGB-552 significantly inhibits the NF - κ B signaling pathway. CIGB-552 can promote apoptosis of tumor cells. CIGB-552 can induce the accumulation of reactive oxygen species (ROS) in tumor cells. CIGB-552 has anti-inflammatory and anti angiogenic effects. CIGB-552 can be used for research on lung cancer and colon cancer.

Purity (HPLC) ≥98.0%

Single impurity≤2%

Peptide content≥75.0%

Amino Acid Composition≤±15%

Bacterial Endotoxins≤50EU/mg

Solubility：H₂O/DMSO

Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.

Storage:Cool dry place( Store at -20°C, away from the light)

Remark:For Research Use Only. Not for human use.

订购联系方式：

南京肽研生物生物科技有限公司

手机号：19961912513(微信同号)

QQ: 2178255659

邮箱：sales@typeptide.com

联系人：顾经理

申明：本产品仅供科研使用，不得用于人体。