versixanthone L 新品

化合物versixanthone L为黄色针状晶体，易溶于氯仿、甲醇。¹³C NMR (100 MHz, Chloroform-d) δ_C 161.8 (C-1), 110.5 (C-2), 140.8 (C-3), 115.5 (C-4), 155.5 (C-4a), 107.1 (C-9a), 159.4 (C-1'), 118.1 (C-2'), 140.7 (C-3'), 170.5 (C-4'), 158.4 (C-4a'), 107.6 (C-9a'), 77.0 (C-5), 76.7 (C-5'), 53.4 (C-13), 53.3 (C-13'), 85.1 (C-10a), 85.0 (C-10a'), 29.4 (C-6), 36.4 (C-7), 29.3 (C-6'), 36.3 (C-7'), 170.5 (C-12), 170.3 (C-12'), 187.3 (C-9), 187.2 (C-9'), 177.8 (C-8), 101.6 (C-8a), 177.5 (C-8'), 101.8 (C-8a'), 18.1 (C-11), 18.1 (C-11').

Reference:Wu GW, Qi X, Mo XM, et al. Structure-based discovery of cytotoxic dimeric tetrahydroxanthones as potential topoisomerase I inhibitors from a marine-derived fungus [J]. European Journal of Medicinal Chemistry, 148 (2018), 268-278.