2883634-40-8 EX-A9589

Name: Eloralintide

Cat#: EX-A9589 Target: Amylin Receptor Pathway: GPCR/G Protein

Chemical Name：L-Tyrosinamide, L-γ-glutamyl-S-(mercaptomethyl)-L-cysteinyl-Lasparaginyl-L-threonyl-L-alanyl-L-threonyl-L-cysteinyl-L-alanyl-Lthreonylglycyl-L-ornithyl-L-leucyl-L-alanyl-L-α-glutamyl-α-methyl-Lphenylalanyl-L-leucyl-L-valyl-L-arginyl-L-seryl-L-seryl-L-asparaginyl-N2- methyl-L-asparaginyl-L-phenylalanylglycyl-L-prolyl-N6-[N-(19-carboxy-1- oxononadecyl)-L-γ-glutamyl-L-γ-glutamyl]-L-lysyl-L-leucyl-L-prolyl-Lprolyl-L-threonyl-L-α-glutamyl-L-valylglycyl-L-seryl-L-asparaginyl-Lthreonyl-, cyclic (2→7)-thioether

Sequence：{γGlu}-Cys-Asn-Thr-Ala-Thr-Cys-Ala-Thr-Gly-{Orn}-Leu-Ala-Glu-{(α-MePhe)}-Leu-Val-Arg-Ser-Ser-Asn-{(N-Me-Asn)}-Phe-Gly-Pro-{Lys(γGlu-γGluC20 diacid)}-Leu-Pro-Pro-Thr-Glu-Val-Gly-Ser-Asn-Thr-Tyr-NH2  (Methylene bridge: Cys2-Cys7)

Sequence  Shortening：{γGlu}-CNTATCATG-{Orn}-LAE-{(α-Me-Phe)}-LVRSSN-{(N-Me-Asn)}-FGP- {Lys(γGlu-γGlu-C20 diacid)}-LPPTEVGSNTY-NH2 (Methylene bridge: Cys2- Cys7)

Molecular  Weight 4526.10 Storage 2 years -20°C powder Formula C201H319N49O65S2 1 month -20°C in solvent CAS No. 2883634-40-8 Synonyms LY3841136; AMY1176 Solubility  (25°C) * In vitro DMSO DMSO : H2O Ethanol N/A Water N/A In vivo （should be freshly  prepared each time）