神经降压素离子配体肽DOTA-NT-20.3/1262311-97-6/DOTA-NT-20.3

Product Name：DOTA-NT-20.3

CAS No.：1262311-97-6

Synonyms：神经降压素离子配体肽DOTA-NT-20.3

Catalog No.：220P305

Brand：Typeptide Biotech（肽研生物）

Description：DOTA-NT-20.3是一种神经降压素（NTS）类似物多肽，也是68Ga离子的配体，是由8个氨基酸和DOTA组成的多肽。68Ga-DOTA-NT-20.3 PET图像显示肿瘤摄取迅速，肿瘤与背景之间对比度高，血液清除速度快，肾脏中积聚适中。68Ga-DOTA-NT-20.3具有良好的药代动力学和生物分布特征，这在患有皮下或原位移植的癌症的小鼠中产生了高质量的PET图像。68Ga-DOTA-NT-20.3显示出与胰腺癌症细胞的NTSR1的特异性结合，并且提供了比18F-FDG更高的腺癌PET检测。

DOTA-NT-20.3 is a neuropeptide (NTS) analog peptide and a ligand for the 68Ga ion, composed of 8 amino acids and DOTA. 68Ga-DOTA-NT-20.3 PET imaging demonstrates rapid tumor uptake, high contrast between tumors and background, fast blood clearance, and moderate accumulation in the kidneys. 68Ga-DOTA-NT-20.3 exhibits favorable pharmacokinetic and biodistribution characteristics, enabling high-quality PET imaging in mice with subcutaneous or orthotopic cancer xenografts. 68Ga-DOTA-NT-20.3 shows specific binding to NTSR1 on pancreatic cancer cells and provides superior PET detection for adenocarcinoma compared to 18F-FDG.

Purity (HPLC) ≥98.0%

Single impurity≤2%

Peptide content≥75.0%

Amino Acid Composition≤±15%

Bacterial Endotoxins≤50EU/mg

Solubility：H₂O/DMSO

Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.

Storage:Cool dry place( Store at -20°C, away from the light)

Remark:For Research Use Only. Not for human use.

订购联系方式：

南京肽研生物生物科技有限公司

手机号：19961912513(微信同号)

QQ: 2178255659

邮箱：sales@typeptide.com

联系人：顾经理

申明：本产品仅供科研使用，不得用于人体。