多肽TAT-ISP/NVG-291 新品

Product Name：NVG-291

CAS No.：N/A

Synonyms：多肽TAT-ISP

Catalog No.：220P296

Brand：Typeptide Biotech（肽研生物）

Description：NVG-291是细胞内σ肽（ISP）的合成肽类似物，用于调节蛋白多糖受体PTPσ，是由35个氨基酸组成的多肽。NVG-291可以通过抑制硫酸软骨素蛋白多糖（CSPGs）和PTPσ之间的相互作用来发挥作用，这两者都抑制少突胶质细胞前体细胞（OPC）的分化和髓鞘再生。在利用溶血磷脂（LPC）和实验性自身免疫性脑脊髓炎（EAE）模型的研究中，ISP的应用与OPC存活、增殖和成熟的增加有关，有助于改善轴突髓鞘再生。

NVG-291 is a synthetic peptide analogue of intracellular sigma peptide (ISP), used to regulate the proteoglycan receptor PTP sigma. It is a peptide composed of 35 amino acids. NVG-291 can exert its effect by inhibiting the interaction between chondroitin sulfate proteoglycans (CSPGs) and PTP σ, both of which inhibit the differentiation of oligodendrocyte precursor cells (OPCs) and myelin regeneration. In studies utilizing lysophosphatidylcholine (LPC) and experimental autoimmune encephalomyelitis (EAE) models, the application of ISP is associated with increased survival, proliferation, and maturation of OPCs, which helps improve axonal myelin regeneration.

Purity (HPLC) ≥98.0%

Single impurity≤2%

Peptide content≥75.0%

Amino Acid Composition≤±15%

Bacterial Endotoxins≤50EU/mg

Solubility：H₂O/DMSO

Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.

Storage:Cool dry place( Store at -20°C, away from the light)

Remark:For Research Use Only. Not for human use.

订购联系方式：

南京肽研生物生物科技有限公司

手机号：19961912513(微信同号)

QQ: 2178255659

邮箱：sales@typeptide.com

联系人：顾经理

申明：本产品仅供科研使用，不得用于人体。