糖尿病相关肽(胰岛淀粉样肽)/122384-88-7/Amylin,amide,human acetate 新品

Product Name：Amylin,amide,human acetate

CAS No.：122384-88-7

Synonyms：糖尿病相关肽(胰岛淀粉样肽)

Catalog No.：106P01

Brand：Typeptide Biotech（肽研生物）

Description：Amylin,amide,human acetate是一种37个氨基酸的多肽，是一种与胰岛素共分泌的胰腺激素，在代谢和葡萄糖稳态中发挥独特的作用。能抑制胰高血糖素分泌，延迟胃排空，并作为饱腹剂。MCF-7 细胞内源性表达人胰淀素受体 CTR1 和 CTR2。 用胰淀素、酰胺、人刺激受体导致产生 cAMP。 Amylin, amide, human (0.001 nM-1000 μM) 导致 EC50 为 35.2±7.5 nM。通过皮下途径注射到不同的瑞士雄性小鼠组中。 观察到游离胰淀素的典型 PK 曲线，半衰期为 23 分钟。

Amylin, amide, human acetate is a 37-amino acid polypeptide, a pancreatic hormone co-secreted with insulin, which plays a unique role in metabolism and glucose homeostasis. It inhibits glucagon secretion, delays gastric emptying, and functions as a satiety agent. MCF-7 cells endogenously express human amylin receptors CTR1 and CTR2. Stimulation of these receptors with amylin, amide, human leads to the production of cAMP. Amylin, amide, human (0.001 nM-1000 μM) resulted in an EC50 of 35.2±7.5 nM. It was administered subcutaneously to different groups of Swiss male mice. A typical PK curve of free amylin was observed, with a half-life of 23 minutes.

Purity (HPLC) ≥98.0%

Single impurity≤2%

Peptide content≥75.0%

Amino Acid Composition≤±15%

Bacterial Endotoxins≤50EU/mg

Solubility：H₂O/DMSO

Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.

Storage:Cool dry place( Store at -20°C, away from the light)

Remark:For Research Use Only. Not for human use.

订购联系方式：

南京肽研生物生物科技有限公司

手机号：19961912513(微信同号)

QQ: 2178255659

邮箱：sales@typeptide.com

联系人：顾经理

申明：本产品仅供科研使用，不得用于人体。