Chiral Tetrahydrofuran Amino Acid Building Block for Peptide and Drug Discovery 新品

Product Description

(S)-2-[(S)-2-Amino-2-(tetrahydrofuran-3-yl)acetamido]-2-(tetrahydrofuran-3-yl)acetic Acid is a highly functionalized chiral amino acid building block designed for peptide chemistry and medicinal chemistry applications.

Featuring two stereochemically defined tetrahydrofuran-containing amino acid units, this compound provides a rigid three-dimensional scaffold that can enhance conformational control, improve molecular recognition, and expand chemical diversity during lead optimization. Its multiple functional groups make it suitable for peptide elongation, analogue synthesis, and structure–activity relationship (SAR) studies.

This building block is particularly valuable for the development of peptide therapeutics, macrocycles, enzyme inhibitors, and other biologically active small molecules.

Key Features

• Chiral amino acid building block

• Dual tetrahydrofuran (THF) motifs

• Conformationally constrained scaffold

• Suitable for peptide synthesis and medicinal chemistry

• Ideal for SAR studies and analogue library construction

• Available for custom synthesis and scale-up

中文产品描述

(S)-2-[(S)-2-氨基-2-(四氢呋喃-3-基)乙酰氨基]-2-(四氢呋喃-3-基)乙酸 是一种具有多个手性中心的高级氨基酸砌块，适用于多肽化学、药物化学及创新药研发。

该化合物含有两个 四氢呋喃（THF） 手性单元，可提供刚性的三维空间构象，有助于提高分子识别能力，并丰富先导化合物的结构多样性。其兼具氨基和羧基等活性官能团，可广泛用于多肽延伸、类似物合成以及构效关系（SAR）研究。

Applications

• Peptide synthesis

• Chiral amino acid building blocks

• Medicinal chemistry

• SAR studies

• Macrocycle synthesis

• Enzyme inhibitor discovery

• Drug discovery research