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  • 4-溴-3-氟甲苯 4-Bromo-3-fluorotoluene

4-溴-3-氟甲苯 4-Bromo-3-fluorotoluene

4-Bromo-3-fluorotoluene
650 1kg 起订
询价 5kg 起订
询价 100kg 起订
广东 更新日期:2025-11-22

广州安纳医药科技有限公司

VIP1年
联系人:LINDA
电话:020-86211473拨打
手机:13925088720 拨打
邮箱:linda@aanpharm.com

产品详情:

中文名称:
4-溴-3-氟甲苯
英文名称:
4-Bromo-3-fluorotoluene
CAS号:
452-74-4
纯度规格:
98%+
产品类别:
中间体

4-溴-3-氟甲苯

英文名称:4-Bromo-3-fluorotoluene,又名3-氟-4-溴甲苯,是一种分子式为C7H6BrF的有机化合物,CAS号为452-74-4,分子量189.02500。常温下为无色至淡黄色液体,密度1.494 g/mL(25℃),沸点95℃(50mmHg),闪点95℉,折射率n20/D 1.53


具体用途

该化合物作为有机合成中间体,通过重氮化溴代Schiemann反应等步骤参与药物合成路径,最终用于生产曲格列汀这类糖尿病治疗药物。其合成路线涉及高温重氮化工艺,可提升生产效率并降低能耗。 ‌

物理性质

4-溴-3-氟甲苯无色透明液体,常温下具有刺激性气味,沸点95℃(50mmHg),密度1.494g/mL(25℃),纯度通常≥98%。


4-Bromo-3-fluorotoluene


English Name: 4-Bromo-3-fluorotoluene, also known as 3-Fluoro-4-bromotoluene, is an organic compound with the molecular formula C₇H₆BrF. Its CAS number is 452-74-4, and its molecular weight is 189.02500. At room temperature, it appears as a colorless to pale yellow liquid, with a density of 1.494 g/mL (at 25°C), a boiling point of 95°C (at 50 mmHg), a flash point of 95°F, and a refractive index of n20/D 1.53.


Specific Applications

This compound serves as an organic synthesis intermediate. It participates in pharmaceutical synthesis pathways through steps such as diazotization bromination and the Schiemann reaction, ultimately used in the production of antidiabetic drugs like Trelegliptin. The synthetic route involves a high-temperature diazotization process, which enhances production efficiency and reduces energy consumption.


Physical Properties

4-Bromo-3-fluorotoluene is a colorless, transparent liquid with a pungent odor at room temperature. It has a boiling point of 95°C (at 50 mmHg), a density of 1.494 g/mL (at 25°C), and a purity typically ≥98%.


4-Bromo;452-74-4;曲格列汀中间体;4-溴-3-氟甲苯;3-fluorotoluene;

公司简介

Guangzhou Aanpharm Technology Co.,Ltd was established in may 2018. It is located in Guangzhou, Guangdong Province, in the pearl river rigion close to hongkong&nansha international port also baiyun internationl airport with most convenient and speedy transportation. Aanpharm is a professional company specializing in developing, producing?and marketing of pharmaceutical intermediates. The company’s products are mainly involved in the field of anti-tumor , epilepsy, rheumatism, cardiovascular and cerebrovascular and have been sold to more than ten countries, such as Europe, India, Japan, South Korea and Southeast Asia. At the present, the company cooperates with three GMP complied factories and two domestic university and R & D center. Guangzhou Aanpharm Technology Co., Ltd. is a company specialized in developing, manufacturing and marketing of Active Pharmaceutical ingredients (APIs) and their intermediates. The company also offers Custom Synthesis services. Aanpharm has established firmed co-operations with several university and R&D centers. Aanpharm provides high quality products, complete documentation and other outstanding supports to the customers. Customers are based in Europe, India, Korea, Japan and other Southeast Asia. Why Choose Us Guangzhou Aanpharm Technology Co., Ltd. is a professional company that specializes in developing, manufacturing, and marketing Active Pharmaceutical Ingredients (APIs) and intermediates. We also provide custom synthesis services to meet our clients’ personalized needs. With advanced technology and equipment, we ensure our products meet the highest quality standards. Our experienced team provides timely and accurate technical support. Choose Aanpharm for innovative solutions and exceptional customer support. Contact Us Get in touch with us and let's work together to achieve your goals. Tel:+86-20-86211473 Mob.:0086-13925088720 Email:sales2@aanpharm.com Add:no.159, jiangtong road, jianggao town, baiyun district,guangzhou,China

成立日期 (1年)
注册资本 50万人民币
员工人数 10-50人
年营业额 ¥ 1000万-5000万
经营模式 贸易,工厂,试剂,定制,服务
主营行业 中间体,医药原料

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