化合物 Methyl α-Linolenyl Fluorophosphonate|T22975|TargetMol

Methyl α-Linolenyl Fluorophosphonate

询价 100mg 起订

500mg 起订

1mg 起订

上海更新日期：2025-11-17

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产品详情:

中文名称：: 化合物 Methyl α-Linolenyl Fluorophosphonate

英文名称：: Methyl α-Linolenyl Fluorophosphonate

品牌：: TargetMol

产地：: 美国

保存条件：: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

产品类别：: 抑制剂

货号：: T22975

Product Introduction

Bioactivity

名称	Methyl α-Linolenyl Fluorophosphonate
描述	Methyl α-Linolenyl Fluorophosphonate is an inhibitor of phospholipases. Methyl α-Linolenyl Fluorophosphonate (MLnFP), an analog of methyl Arachidonyl Fuorophosphonate (MAFP), has not been completely investigated for its pharmacological activity.
体外活性	In vitro: MethylArachidonyl Fluorophosphonate (MAFP) was reported to be a selective, active-site directed, irreversible inhibitor of cytosolic phospholipase A2 (cPLA2). MAFP could also potently inhibit the Ca2+-independent cytosolic phospholipase A2 (iPLA2) in a concentration-dependent manner. Such inhibition was not reversed upon extensive dilution of the enzyme into the assay mixture. The Preincubation of iPLA2 with MAFP led to a linear and time-dependent inactivation of enzyme activity, and the enzyme was protected from inactivation by the reversible inhibitor. The ability of MAFP to inhibit the iPLA 2 indicated that this enzyme proceeded via an acyl-enzyme intermediate. Further testing showed that MAFP could not inhibit the CoA-dependent acyltransferase, arachidonoyI-CoA synthetase, or CoA-independent transacylase activities. Therefore, MAFP was not a general inhibitor for enzymes acting on arachidonoyi substrates [1].
存储条件	Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice/Shipping at ambient temperature.
溶解度	Ethanol : ≤5 mg/mL, Sonication is recommended. DMSO : 5 mg/mL (14.52 mM), Sonication is recommended.
关键字	Methyl αLinolenyl Fluorophosphonate \| Methyl a-Linolenyl Fluorophosphonate \| Methyl α-Linolenyl Fluorophosphonate \| Methyl α Linolenyl Fluorophosphonate \| Methyl alpha-Linolenyl Fluorophosphonate

Methyl α-Linolenyl Fluorophosphonate|TargetMol

TargetMol Chemicals Inc. 总部位于马萨诸塞州波士顿，致力于为全球生化领域科学家的研究提供专业的产品和服务。TargetMol?品牌的客户群分布于40多个国家和地区，已发展成为全球知名的化合物库和小分子化合物研究供应商。 TargetMol?可提供160多种满足不同需求的化合物库，以及多种类型的生化试剂产品，包括12000多种抑制剂、16000多种天然产物和各类多肽、抗体、生命科学试剂盒等，此外，我们还建设有CADD（计算机辅助药物设计）研究中心、药理实验室、药化合成平台三大技术中心，全方位满足客户的定制需求。凭借我们优质的产品和服务、快速高效的全球供应链和专业的技术支持，我们将有效帮助您缩短研发周期，取得更成功的结果。

成立日期	(13年)
注册资本	589.8595万人民币
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年营业额	￥ 1亿以上
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主营行业	中间体,天然产物,生物化工,化学试剂,生物技术服务

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