小鼠DLL3蛋白, His Tag

Mouse DLL3 Protein, His Tag (HPLC verified)

分子别名（Synonym）

Delta3,delta-like 3 (Drosophila),delta-like protein 3,DLL3,Pudgy,SCDO1,SCDO1delta3

表达区间及表达系统（Source）

Mouse DLL3, His Tag (DL3-M52H9) is expressed from human 293 cells (HEK293). It contains AA Ala 25 - Arg 488 (Accession # O88516-1).

Predicted N-terminus: Asp

蛋白结构（Molecular Characterization）

This protein carries a polyhistidine tag at the C-terminus and a fusion design at the N-terminus. The protein has a calculated MW of 118 kDa. The protein migrates as 100-115 kDa under reducing (R) condition (SDS-PAGE).

内毒素（Endotoxin）

Less than 1.0 EU per μg by the LAL method / rFC method.

纯度（Purity）

>95% as determined by SDS-PAGE.

制剂（Formulation）

Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

Contact us for customized product form or formulation.

重构方法（Reconstitution）

Please see Certificate of Analysis for specific instructions.

For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

存储（Storage）

For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:

-20°C to -70°C for 12 months in lyophilized state;

-70°C for 3 months under sterile conditions after reconstitution.

背景介绍

Delta样蛋白3（DLL3）属于Notch配体的Delta/Serrate/Lag-2（DSL）蛋白家族成员，是一种跨膜蛋白。该蛋白可能参与引导神经元沿特定分化途径发育，并在体节形成过程中调控体节边界的建立。DLL3蛋白在肿瘤细胞表面表达，但在正常成体组织中不表达。