食蟹猴血清白蛋白Albumin Protein, His Tag

Cynomolgus Serum Albumin Protein, His Tag (MALS & SPR verified)

分子别名（Synonym）

Serum albumin, ALB, Alb

表达区间及表达系统（Source）

Cynomolgus Serum Albumin, His Tag (CSA-C52H4) is expressed from human 293 cells (HEK293). It contains AA Asp 25 - Ala 608 (Accession # A2V9Z4-1).

Predicted N-terminus: Asp 25

蛋白结构（Molecular Characterization）

This protein carries a polyhistidine tag at the C-terminus.

The protein has a calculated MW of 67.9 kDa. The protein migrates as 66 kDa under reducing (R) condition (SDS-PAGE).

内毒素（Endotoxin）

Less than 1.0 EU per μg by the LAL method / rFC method.

纯度（Purity）

>95% as determined by SDS-PAGE.

>90% as determined by SEC-MALS.

制剂（Formulation）

Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

Contact us for customized product form or formulation.

重构方法（Reconstitution）

Please see Certificate of Analysis for specific instructions.

For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

存储（Storage）

For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:

-20°C to -70°C for 12 months in lyophilized state;

-70°C for 3 months under sterile conditions after reconstitution.

背景介绍

血清白蛋白（简称SA或ALB）是血浆中的主要蛋白质，对水分子、钙离子、钠离子、钾离子、脂肪酸、激素、胆红素及药物均具有良好的结合能力。其主要功能是调节血液胶体渗透压。作为血浆中主要的锌转运蛋白，血清白蛋白通常结合约80%的血浆锌。白蛋白的变异结构可能导致锌结合能力增强，进而引起血液中锌浓度无症状性升高。血清白蛋白缺陷可引发家族性白蛋白异常性高甲状腺素血症——这是一种因白蛋白与T4结合亲和力增高导致的甲状腺功能正常型高甲状腺素血症，也是白种人群中最常见的遗传性甲状腺功能正常型高甲状腺素血症病因。