人BCMA / TNFRSF17蛋白, His Tag

APC-Labeled Human BCMA / TNFRSF17 Protein, His Tag (Site-specific conjugation)

分子别名（Synonym）

TNFRSF17,CD269,BCM,BCMA

表达区间及表达系统（Source）

APC-Labeled Human BCMA, His Tag (BCA-HA2H5) is produced via conjugation of APC to Human BCMA, His Tag with a new generation site-specific technology under optimal conditions with a proprietary technology. Human BCMA, His Tag is expressed from human 293 cells (HEK293). It contains AA Met 1 - Ala 54 (Accession # Q02223-1).

Predicted N-terminus: Met 1

蛋白结构（Molecular Characterization）

This protein carries a polyhistidine tag at the C-terminus.

The protein has a calculated MW of 9.6 kDa.

偶联（Conjugate）

APC

Excitation Wavelength: 640 nm

Emission Wavelength: 661 nm

应用说明（Application）

Please note that this product is NOT compatible to streptavidin detection system.

制剂（Formulation）

Lyophilized from 0.22 μm filtered solution in PBS, 0.5% BSA, pH7.4 with trehalose as protectant.

Contact us for customized product form or formulation.

重构方法（Reconstitution）

Please see Certificate of Analysis for specific instructions.

For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

存储（Storage）

For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Please protect from light and avoid repeated freeze-thaw cycles.

This product is stable after storage at:

-20°C to -70°C for 12 months in lyophilized state;

-70°C for 3 months under sterile conditions after reconstitution.

背景介绍

肿瘤坏死因子受体超家族成员17（TNFRSF17）亦称B细胞成熟蛋白（BCMA）或CD269抗原，是TNF受体超家族成员。该蛋白包含一个TNFR-Cys重复结构域，在成熟B细胞中表达，但不存在于T细胞或单核细胞。TNFRSF17作为TNFSF13B/BLyS/BAFF与TNFSF13/APRIL的受体，可促进B细胞存活并参与体液免疫调节，其功能机制涉及NF-κB与JNK信号通路的激活。