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网站主页 化工产品目录 生物化工 生化试剂 eukaryotic translation elongation factor 1 alpha 1 (EEF1A1) (387-394) [Multiple species] 化合物 eukaryotic translation elongation factor 1 alpha 1 (EEF1A1) (387-394) [Multiple species]
  • 化合物 eukaryotic translation elongation factor 1 alpha 1 (EEF1A1) (387-394) [Multiple species]|T22774|TargetMol

化合物 eukaryotic translation elongation factor 1 alpha 1 (EEF1A1) (387-394) [Multiple species]|T22774|TargetMol

eukaryotic translation elongation factor 1 alpha 1 (EEF1A1) (387-394) [Multiple species]
￥483 1mg 起订
￥1383 5mg 起订
￥2283 10mg 起订
上海 更新日期：2025-11-17

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产品详情:

中文名称：
化合物 eukaryotic translation elongation factor 1 alpha 1 (EEF1A1) (387-394) [Multiple species]
英文名称：
eukaryotic translation elongation factor 1 alpha 1 (EEF1A1) (387-394) [Multiple species]
品牌：
TargetMol
产地：
美国
保存条件：
Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
产品类别：
抑制剂
货号：
T22774

Product Introduction

Bioactivity

名称eukaryotic translation elongation factor 1 alpha 1 (EEF1A1) (387-394) [Multiple species]
描述eukaryotic translation elongation factor 1 alpha 1 (EEF1A1) encodes an isoform of the alpha subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. This isoform (alpha 1) is expressed in the brain, placenta, lung, liver, kidney, and pancreas, and the other isoform (alpha 2) is expressed in the brain, heart, and skeletal muscle. This isoform is identified as an autoantigen in 66% of patients with Felty syndrome. This gene has been found to have multiple copies on many chromosomes, some of which, if not all, represent different pseudogenes1.
体外活性There are two forms of eEF1A in eukaryotes, eEF1A1 and eEF1A2, both of which possess the same role in protein synthesis2. eEF1A2 was reported to be exclusively expressed in the brain, heart, and skeletal muscle, whereas eEF1A1 is well known to be ubiquitously expressed3. Tetraploid cells produced by impaired chromosomal condensation are eliminated by a novel type of cell death different from caspase-dependent apoptosis. Cell death was associated with the downregulation of eukaryotic translation elongation factor-1 a 1 (eEF1A1/EF-1a) expression in conjunction with the accumulation of its mRNA in processing bodies (P bodies). Importantly, expression of exogenous eEF1A1 was shown to inhibit the caspase-independent cell death, and similar cell death was observed after inducing the expression of short hairpin RNA speci?c for eEF1A12.
存储条件Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
溶解度DMSO : ≥91.8 mg/mL, Sonication is recommended.
关键字eukaryotic translation elongation factor 1 alpha 1 (EEF-1A1) (387-394) [Multiple species] | eukaryotic translation elongation factor 1 alpha 1 (EEF1A1) (387394) [Multiple species] | eukaryotic translation elongation factor 1 alpha 1 (EEF1A1) (387 394) [Multiple species]
eukaryotic translation elongation factor 1 alpha 1 (EEF1A1) (387-394) [Multiple species]|TargetMol

公司简介

TargetMol Chemicals Inc. 总部位于马萨诸塞州波士顿，致力于为全球生化领域科学家的研究提供专业的产品和服务。TargetMol?品牌的客户群分布于40多个国家和地区，已发展成为全球知名的化合物库和小分子化合物研究供应商。 TargetMol?可提供160多种满足不同需求的化合物库，以及多种类型的生化试剂产品，包括12000多种抑制剂、16000多种天然产物和各类多肽、抗体、生命科学试剂盒等，此外，我们还建设有CADD（计算机辅助药物设计）研究中心、药理实验室、药化合成平台三大技术中心，全方位满足客户的定制需求。 凭借我们优质的产品和服务、快速高效的全球供应链和专业的技术支持，我们将有效帮助您缩短研发周期，取得更成功的结果。

成立日期 (13年)
注册资本 589.8595万人民币
员工人数 100-500人
年营业额 ￥ 1亿以上
经营模式 贸易,工厂,试剂,定制,服务
主营行业 中间体,天然产物,生物化工,化学试剂,生物技术服务

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