谷氨酸脱羧酶 65(524-543)/152468-44-5/GAD65 (524-543)

Product Name：GAD65 (524-543)

CAS No.：152468-44-5

Synonyms：谷氨酸脱羧酶 65(524-543)

Catalog No.：220P094

Brand：Typeptide Biotech（肽研生物）

Description：GAD65 (524-543)是谷氨酸脱羧酶 65 (GAD65) 的氨基酸 524 至 543 片段。GAD65 (524-543)是该胰岛抗原的首批片段之一，可在自发性自身免疫性糖尿病的非肥胖糖尿病 (NOD) 小鼠模型中诱导增殖性 T 细胞反应。该肽是对自发产生的糖尿病 T 细胞克隆 BDC2.5 的特异性刺激，可能亲和力较低。 p524-543 免疫增加了 NOD 小鼠对 BDC2.5 T 细胞过继转移诱导的 1 型糖尿病的易感性。

GAD65 (524-543) is the amino acid 524 to 543 fragment of glutamic acid decarboxylase 65 (GAD65). GAD65 (524-543) is one of the first fragments of this islet antigen, which can induce proliferative T cell response in the non obese diabetes (NOD) mouse model of spontaneous autoimmune diabetes. This peptide is a specific stimulus to spontaneously generated diabetes T cell clone BDC2.5, and may have low affinity. Immunization with p524-543 increased the susceptibility of NOD mice to type 1 diabetes induced by adoptive transfer of BDC2.5 T cells.

Purity (HPLC) ≥98.0%

Single impurity≤2%

Peptide content≥75.0%

Amino Acid Composition≤±15%

Bacterial Endotoxins≤50EU/mg

Solubility：H₂O/DMSO

Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.

Storage:Cool dry place( Store at -20°C, away from the light)

Remark:For Research Use Only. Not for human use.

订购联系方式：

南京肽研生物生物科技有限公司

手机号：19961912513(微信同号)

QQ: 2178255659

邮箱：sales@typeptide.com

联系人：顾经理

申明：本产品仅供科研使用，不得用于人体。