FOXP3抑制剂多肽/1319725-20-6/Peptide P60

Product Name：Peptide P60

CAS No.：1319725-20-6

Synonyms：FOXP3抑制剂多肽

Catalog No.：220P058

Brand：Typeptide Biotech（肽研生物）

Description：Peptide P60是一种FOXP3抑制剂多肽，是由15氨基酸组成的多肽。Peptide P60 能够进入细胞，抑制 FOXP3 的核转位，并降低其抑制转录因子 NF-κB 和 NFAT 的能力。Peptide P60 能够抑制小鼠和人类来源的调节性 T 细胞 (Treg) 的免疫抑制活性，并在体外增强效应 T 细胞的刺激。Peptide P60 可诱发一种淋巴增生性自身免疫综合征，其病理表现与报道的缺乏功能性 Foxp3 的斑驳鼠相似。Peptide P60 可以提高癌症和病毒疫苗的免疫原性。

Peptide P60 is a FOXP3 inhibitor peptide composed of 15 amino acids. Peptide P60 can enter cells, inhibit the nuclear translocation of FOXP3, and reduce its ability to inhibit transcription factors NF - κ B and NFAT. Peptide P60 can inhibit the immunosuppressive activity of regulatory T cells (Tregs) derived from mice and humans, and enhance the stimulation of effector T cells in vitro. Peptide P60 can induce a lymphoproliferative autoimmune syndrome, whose pathological manifestations are similar to those reported in mottled mice lacking functional Foxp3. Peptide P60 can enhance the immunogenicity of cancer and viral vaccines.

Purity (HPLC) ≥98.0%

Single impurity≤2%

Peptide content≥75.0%

Amino Acid Composition≤±15%

Bacterial Endotoxins≤50EU/mg

Solubility：H₂O/DMSO

Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.

Storage:Cool dry place( Store at -20°C, away from the light)

Remark:For Research Use Only. Not for human use.

订购联系方式：

南京肽研生物生物科技有限公司

手机号：19961912513(微信同号)

QQ: 2178255659

邮箱：sales@typeptide.com

联系人：顾经理

申明：本产品仅供科研使用，不得用于人体。