RAVER2抗体;RAVER2 Antibody—艾普蒂 新品

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     Western blot analysis of RAVER2 expression in 293T cell lysate.    

  
  

The RAVER2 (RNA-associated vesicle protein 2) antibody is a research tool designed to study the RAVER2 protein, a member of the RAVER family implicated in RNA binding and regulatory processes. RAVER2 is structurally characterized by conserved RNA recognition motifs (RRMs) and interacts with other RNA-binding proteins, suggesting roles in mRNA processing, transport, or stability. It has been linked to cellular stress responses, potentially influencing the formation of stress granules—dynamic ribonucleoprotein complexes that modulate translation during environmental stress.

Studies indicate RAVER2 may regulate gene expression by bridging RNA molecules with chromatin-modifying complexes, affecting transcriptional outcomes. Its dysregulation is explored in contexts like cancer and neurodegenerative diseases, where RNA metabolism disruptions are common. The RAVER2 antibody, typically a polyclonal or monoclonal reagent derived from rabbits or mice, is utilized in techniques such as Western blotting, immunofluorescence, and immunoprecipitation to detect protein expression, subcellular localization (e.g., cytoplasmic or nuclear distribution), and molecular interactions.

This antibody aids in elucidating RAVER2’s functional pathways, including its interplay with other RNA-binding proteins and its potential as a biomarker or therapeutic target. Researchers prioritize antibody validation via knockout controls to ensure specificity, given the protein’s low abundance in certain tissues. Overall, it serves as a critical probe in RNA biology and disease mechanism studies.