InhibinbetaA抗体;InhibinbetaA Antibody—艾普蒂 新品

+ +

•  

   

     All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.    

  
  

•  

   

     Western blot analysis of Inhibin beta A expression in Human fetal brain lysate.    

  
  

**Background of Inhibin Beta A Antibody**

Inhibin beta A (INHβA) is a subunit of inhibins and activins, which belong to the transforming growth factor-beta (TGF-β) superfamily. Inhibins are heterodimeric hormones composed of an alpha subunit and either a beta A (INHβA) or beta B (INHβB) subunit, while activins are homodimers or heterodimers of beta subunits. These proteins play critical roles in regulating follicle-stimulating hormone (FSH) secretion, reproductive physiology, and cellular processes like proliferation and apoptosis.

The inhibin beta A antibody is a targeted tool designed to detect and quantify the INHβA subunit in various biological samples. It is widely used in research applications such as Western blotting, immunohistochemistry (IHC), and ELISA to study the expression and localization of INHβA in tissues, particularly in reproductive organs (e.g., ovaries, testes) and endocrine-related pathologies. This antibody is essential for investigating conditions like granulosa cell tumors, premature ovarian insufficiency, and certain cancers where INHβA dysregulation is implicated.

Due to its specificity, the antibody helps distinguish inhibin A (α-βA dimer) from other isoforms and activins (e.g., activin A, βA-βA). Cross-reactivity with INHβA in humans and common model organisms (e.g., mice, rats) enhances its utility in translational studies. Validated for sensitivity and specificity, the inhibin beta A antibody serves as a reliable reagent in both basic research and clinical diagnostics, aiding in understanding reproductive health, cancer mechanisms, and therapeutic targeting.