Mov10抗体;Mov10 Antibody—艾普蒂 新品

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     All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.    

  
  

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     All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.    

  
  

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     All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.    

  
  

The MOV10 antibody is a crucial tool for studying the MOV10 protein, an RNA helicase involved in various cellular processes. MOV10 (Moloney leukemia virus 10 homolog) belongs to the UPF1-like helicase family and plays roles in RNA interference (RNAi), microRNA (miRNA) processing, retrotransposon silencing, and antiviral defense. It interacts with components of the RNA-induced silencing complex (RISC) and participates in post-transcriptional gene regulation by unwinding RNA secondary structures or displacing proteins bound to RNA. MOV10 also restricts retroviral replication by inhibiting reverse transcription and viral DNA integration.

Antibodies targeting MOV10 are widely used in techniques like Western blotting, immunofluorescence (IF), and immunoprecipitation (IP) to investigate its expression, localization, and molecular interactions. These antibodies are typically raised against specific epitopes, such as the N-terminal or C-terminal regions of the protein, and are available in monoclonal or polyclonal formats from various host species (e.g., rabbit, mouse). Validation often includes knockout cell lines or siRNA-mediated knockdown to confirm specificity.

Research applications of MOV10 antibodies span virology, neurobiology, and cancer biology, as MOV10 dysfunction is linked to neurological disorders, viral susceptibility, and tumorigenesis. Studies also explore its role in maintaining genomic stability by suppressing mobile genetic elements. Overall, MOV10 antibodies are vital for dissecting the protein's multifaceted contributions to RNA metabolism and cellular homeostasis.