EB3抗体;EB3 Antibody—艾普蒂新品

Rabbit Monoclonal EB3 Antibody

询价 20μl 起订

50μl 起订

100μl 起订

上海更新日期：2025-05-30

上海切尔齐生物科技有限公司

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联系人：周经理

电话：027-19371278702拨打

手机：18008634902 拨打

邮箱：nuodina88@163.com

产品详情:

中文名称：: EB3抗体

英文名称：: Rabbit Monoclonal EB3 Antibody

品牌：: 艾普蒂

产地：: 武汉

保存条件：: Stored at -20°C for 8339 year. Avoid repeated freeze / thaw cycles.

产品类别：: 抗体

重组：: 否

应用：: WB: IHC-P: IHC-F: ICC/IF: IP:FC:ChIP: ELISA

种属反应性：: Human,Mouse,Rat

宿主：: Rabbit

偶联物：: 无

靶点：: EB3

验证与应用

应用及物种

WB	咨询技术	Human,Mouse,Rat
IF	咨询技术	Human,Mouse,Rat
IHC	IHC:1/100-1/200;IHF:1/50-1/200	Human,Mouse,Rat
ICC	1/50-1/200	Human,Mouse,Rat
FCM	1/20-1/100	Human,Mouse,Rat
Elisa	咨询技术	Human,Mouse,Rat

产品详情

Aliases	EB3; EBF3; MAPRE3; RP/EB Family; RP3;;MAPRE3
WB Predicted band size	32 kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	A synthesized peptide derived from human MAPRE3
Formulation	Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol.

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Western blot analysis of EB3 expression in Ratmuscle cell lysate.

参考文献

以下是关于EB3抗体的3篇代表性文献(注：文献信息为示例性质，实际引用需核实原文)：

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1. **"Microtubule plus-end tracking proteins and their roles in cell division"**

- **作者**: Akhmanova A., Steinmetz M.O.

- **摘要**: 本文综述了微管正端追踪蛋白(+TIPs)家族的功能，重点讨论了EB3(End-Binding Protein 3)在细胞分裂和迁移中的作用，并提及特异性抗体在活细胞成像中用于追踪EB3动态定位的应用。

2. **"EB3 regulates microtubule dynamics at the cell cortex and is required for neurite outgrowth"**

- **作者**: Hoogenraad C.C., et al.

- **摘要**: 研究通过EB3抗体的免疫荧光技术，揭示了EB3在神经元发育中调控微管生长方向的机制，证明其缺失导致神经突延伸障碍。

3. **"Characterization of EB3-specific antibodies for studying microtubule dynamics"**

- **作者**: Galjart N., et al.

- **摘要**: 本文报道了针对EB3蛋白的多克隆和单克隆抗体的开发，验证了其特异性及在免疫印迹(Western blot)和免疫共沉淀(Co-IP)中的应用，为EB3功能研究提供工具支持。

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如需具体文献，建议通过PubMed或Google Scholar以关键词“EB3 antibody”、“EB3 microtubule”检索并筛选近年高引论文。

背景信息

EB3 antibody targets the Epstein-Barr virus nuclear antigen 3 (EBNA3), a latent-phase protein encoded by the Epstein-Barr virus (EBV), a herpesvirus linked to malignancies like Burkitt’s lymphoma, nasopharyngeal carcinoma, and lymphoproliferative disorders. EBNA3. comprising EBNA3A, EBNA3B, and EBNA3C, regulates viral latency and host cell transformation by modulating gene expression and immune evasion. EB3 antibodies, often generated against EBNA3C (the most studied isoform), serve as critical tools in EBV research, enabling detection of viral proteins in infected cells via techniques like immunofluorescence, Western blotting, and immunohistochemistry.

Clinically, EB3 antibodies aid in diagnosing EBV-associated diseases, monitoring viral activity, and studying oncogenic mechanisms. Their role extends to exploring EBV’s interplay with host immunity, as EBNA3C disrupts antigen presentation and apoptosis pathways. Research using EB3 antibodies has revealed EBNA3's involvement in epigenetic regulation and cell cycle manipulation, advancing therapeutic strategies targeting EBV persistence. However, cross-reactivity with homologous host proteins remains a challenge, necessitating rigorous validation. Overall, EB3 antibodies are indispensable for unraveling EBV biology and developing diagnostics or treatments for EBV-driven pathologies.

EB3抗体;EB3;EB3 Antibody;

公司简介

生物技术有限公司

成立日期	(2年)
注册资本	20万人民币
员工人数	1-10人
年营业额	￥ 100万以内
经营模式	贸易,工厂,试剂,定制,服务
主营行业	抗体,植物生物技术,细胞培养,蛋白组学