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  • DAZAP1抗体;DAZAP1 Antibody—艾普蒂
  • DAZAP1抗体;DAZAP1 Antibody—艾普蒂
  • DAZAP1抗体;DAZAP1 Antibody—艾普蒂

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DAZAP1抗体;DAZAP1 Antibody—艾普蒂

Rabbit Monoclonal DAZAP1 Antibody
询价 20μl 起订
50μl 起订
100μl 起订
上海 更新日期：2025-05-30

上海切尔齐生物科技有限公司

非会员
联系人：周***
电话：027***
手机：180***
邮箱：nuo***

产品详情:

中文名称：
DAZAP1抗体
英文名称：
Rabbit Monoclonal DAZAP1 Antibody
品牌：
艾普蒂
产地：
武汉
保存条件：
Stored at -20°C for 8250 year. Avoid repeated freeze / thaw cycles.
产品类别：
抗体
重组：
否
应用：
WB: IHC-P: IHC-F: ICC/IF: IP:FC:ChIP: ELISA
种属反应性：
Human,Mouse,Rat
宿主：
Rabbit
偶联物：
无
靶点：
DAZAP1

验证与应用

应用及物种
WB咨询技术 Human,Mouse,Rat
IF咨询技术 Human,Mouse,Rat
IHC咨询技术 Human,Mouse,Rat
ICC技术咨询 Human,Mouse,Rat
FCM咨询技术 Human,Mouse,Rat
Elisa咨询技术 Human,Mouse,Rat
   

产品详情

AliasesDAZ associated protein 1; Dazap1;;DAZ associated protein 1
WB Predicted band size43 kDa
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman,Mouse,Rat
ImmunogenA synthesized peptide derived from human DAZ associated protein 1
FormulationPurified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol.

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       Western blot analysis of DAZAP1 expression in Jurkat cell lysate.    


           

参考文献

以下是3篇关于DAZAP1抗体的代表性文献(示例性内容，建议根据实际研究核实)：

1. **文献名称**: *DAZAP1 modulates splicing and transcriptional activity in neurodevelopment*

**作者**: Zhang Y, et al.

**摘要**: 本研究利用DAZAP1特异性抗体，通过免疫荧光和Western blot技术，揭示了DAZAP1在小鼠大脑皮层神经元中的亚细胞定位，并发现其通过调控RNA剪接参与神经突触形成。

2. **文献名称**: *DAZAP1 acts as a tumor suppressor in colorectal cancer by regulating β-catenin signaling*

**作者**: Wang L, et al.

**摘要**: 作者通过DAZAP1抗体进行免疫组化分析，发现DAZAP1在结直肠癌组织中表达下调，并证明其缺失通过激活Wnt/β-catenin通路促进肿瘤侵袭。

3. **文献名称**: *DAZAP1 interacts with PABPC1 to mediate mRNA translational control*

**作者**: Chen X, et al.

**摘要**: 该研究利用DAZAP1抗体进行免疫共沉淀(Co-IP)实验，发现DAZAP1与多聚腺苷酸结合蛋白PABPC1相互作用，共同调控靶mRNA的翻译效率。

**提示**：以上文献信息为示例，实际文献需通过PubMed或Google Scholar以“DAZAP1 antibody”为关键词检索，并筛选涉及抗体具体应用的论文(如检测、定位或功能研究)。

       

背景信息

The DAZAP1 (Deleted in Azoospermia Associated Protein 1) antibody is a tool used to study the DAZAP1 protein, a ubiquitously expressed RNA-binding protein implicated in mRNA metabolism, including splicing, transport, and translation. DAZAP1 contains two RNA recognition motifs (RRMs) and interacts with various proteins, such as members of the DAZ (Deleted in Azoospermia) family, which are critical for germ cell development. It plays roles in cellular processes like cell proliferation, differentiation, and stress response, with dysregulation linked to cancers, neurodevelopmental disorders, and infertility.

DAZAP1 antibodies, typically generated in rabbits or mice using immunogenic peptide sequences or recombinant protein fragments, enable detection of DAZAP1 in techniques like Western blotting, immunohistochemistry, and immunofluorescence. These antibodies help elucidate DAZAP1's expression patterns, subcellular localization (nucleus and cytoplasm), and interactions in normal and diseased tissues. Research using DAZAP1 antibodies has revealed its tumor-suppressive or oncogenic roles in context-dependent malignancies and its involvement in neural development. Such studies underscore its potential as a biomarker or therapeutic target. Validation steps, including knockout controls, ensure antibody specificity for reliable experimental outcomes.

       
DAZAP1抗体;DAZAP1;DAZAP1 Antibody;

公司简介

生物技术有限公司

成立日期 (2年)
注册资本 20万人民币
员工人数 1-10人
年营业额 ￥ 100万以内
经营模式 贸易,工厂,试剂,定制,服务
主营行业 抗体,植物生物技术,细胞培养,蛋白组学

DAZAP1抗体相关厂家报价

  • 抗CRF抗体
  • 抗CRF抗体
  • 维百奥（北京）生物科技有限公司 VIP
  • 2025-12-29
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