EphrinB2抗体;EphrinB2 Antibody—艾普蒂

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     All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.    

  
  

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     All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.    

  
  

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     All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.    

  
  

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     Immunofluorescent analysis using the Antibody at 1:50 dilution.    

  
  

EphrinB2 antibodies are tools used to study the EphrinB2 protein, a key member of the Eph receptor tyrosine kinase signaling pathway. EphrinB2 is a transmembrane ligand that binds to EphB receptors, mediating bidirectional signaling critical for cell-cell communication. It plays essential roles in embryonic development, angiogenesis, and tissue patterning. Notably, EphrinB2 is a marker for arterial endothelial cells and regulates vascular morphogenesis by interacting with EphB4 receptors in veins. Dysregulation of EphrinB2-EphB4 signaling is implicated in pathological conditions, including cancer, cardiovascular diseases, and neurological disorders.

EphrinB2 antibodies are widely utilized in research to detect protein _expression (via Western blotting, immunofluorescence, or immunohistochemistry) and to modulate EphrinB2 function in experimental models. They help elucidate mechanisms in tumor angiogenesis, metastasis, and vascular remodeling. Some antibodies block ligand-receptor interactions, enabling functional studies, while others serve as diagnostic markers. Challenges remain in ensuring antibody specificity due to structural similarities within the Ephrin family. Recent studies explore therapeutic potential, such as targeting EphrinB2 in anti-angiogenic cancer therapies or tissue regeneration. However, translating these findings requires addressing off-target effects and optimizing delivery strategies.