Hsp20抗体;Hsp20 Antibody—艾普蒂

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     Western blot analysis of Hsp20 expression in mouse skeletal muscle lysate.    

  
  

**Background of Hsp20 Antibody**

Heat shock protein 20 (Hsp20), a member of the small heat shock protein (sHSP) family, is a molecular chaperone that plays a critical role in cellular stress responses. It assists in protein folding, prevents aggregation of denatured proteins, and supports cell survival under stress conditions such as heat, oxidative stress, or ischemia. Hsp20 is particularly notable for its cardioprotective functions, including modulation of apoptosis, contractility, and vascular smooth muscle relaxation, making it a focus in cardiovascular research.

Hsp20 antibodies are essential tools for detecting and quantifying Hsp20 expression in tissues or cells. They are widely used in techniques like Western blotting, immunohistochemistry, and immunofluorescence to study Hsp20's regulatory mechanisms, such as phosphorylation-dependent interactions. Research has linked Hsp20 dysregulation to pathologies like heart failure, neurodegenerative diseases, and cancer, positioning it as a potential biomarker or therapeutic target.

The antibody's specificity enables exploration of Hsp20's role in stress adaptation, disease mechanisms, and signaling pathways. Its high conservation across species also supports translational studies using animal models. By leveraging Hsp20 antibodies, scientists aim to uncover novel therapeutic strategies targeting Hsp20-associated pathways in human diseases.