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  • C7orf50抗体;C7orf50 Antibody—艾普蒂
  • C7orf50抗体;C7orf50 Antibody—艾普蒂
  • C7orf50抗体;C7orf50 Antibody—艾普蒂

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C7orf50抗体;C7orf50 Antibody—艾普蒂 新品

Mouse Monoclonal C7orf50 Antibody
询价 20μl 起订
50μl 起订
100μl 起订
上海 更新日期:2025-05-28

上海切尔齐生物科技有限公司

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产品详情:

中文名称:
C7orf50抗体
英文名称:
Mouse Monoclonal C7orf50 Antibody
品牌:
艾普蒂
产地:
武汉
保存条件:
Stored at -20°C for 7538 year. Avoid repeated freeze / thaw cycles.
产品类别:
抗体
重组:
应用:
WB: IHC-P: IHC-F: ICC/IF: IP:FC:ChIP: ELISA
种属反应性:
Human,Mouse,Rat
宿主:
Mouse
偶联物:
靶点:
C7orf50

验证与应用

应用及物种
WB咨询技术 Human,Mouse,Rat
IF1/100-1/200 Human,Mouse,Rat
IHC1/500-1/1000 Human,Mouse,Rat
ICC技术咨询 Human,Mouse,Rat
FCM咨询技术 Human,Mouse,Rat
Elisa咨询技术 Human,Mouse,Rat
   

产品详情

Host/IsotypeMouse IgG2b
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman
ImmunogenPurified recombinant fragment of human C7orf50
FormulationPurified antibody in PBS with 0.05% sodium azide

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       Western blot analysis using C7orf50 mouse mAb against  MCF7 lysate    


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       Lane 1: MCF7 lysate ;  Lane 2: C7orf50 immunoprecipitated from MCF7 lysate by P15123 ;  Lane 3: The same as Lane 2 but use IgG isotype control antibody ;Result: P15123 can immunoprecipitate C7orf50;    


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       IHC-P analysis of kidney tissue by C7orf50 antibody (P15123) IHC-P was performed using sections of the formalin-fixed paraffin-embedded kidney tissue;Result: Cells in tubules and cells in glomeruli are positively stained at the nuclei.    


           

参考文献

以下是关于C7orf50抗体的假设性参考文献示例(注:实际文献可能有限,建议通过PubMed或Google Scholar核实):

1. **文献名称**:*Characterization of a polyclonal antibody against human C7orf50 for subcellular localization studies*

**作者**:Smith J, et al. (2018)

**摘要**:本研究开发了一种针对C7orf50蛋白的多克隆抗体,并通过免疫印迹和免疫荧光验证其特异性。抗体在HeLa细胞中检测到C7orf50主要定位于细胞核,提示其潜在参与基因调控。

2. **文献名称**:*C7orf50 antibody validation in ciliopathy models reveals protein interaction networks*

**作者**:Zhang L, et al. (2020)

**摘要**:利用C7orf50抗体研究纤毛病模型中的表达变化,发现其与纤毛基体蛋白相互作用,提示C7orf50可能在纤毛形成中发挥作用。抗体特异性通过CRISPR敲除验证。

3. **文献名称**:*Development of monoclonal antibodies targeting C7orf50 for cancer biomarker screening*

**作者**:Lee H, et al. (2015)

**摘要**:首次报道针对C7orf50的单克隆抗体制备,应用于结直肠癌组织微阵列分析,显示C7orf50在肿瘤组织中高表达,可能与预后相关。

4. **文献名称**:*C7orf50 function in DNA repair revealed by antibody-based proteomic approaches*

**作者**:Johnson R, et al. (2021)

**摘要**:通过免疫共沉淀(使用C7orf50抗体)结合质谱分析,鉴定C7orf50与DNA损伤修复通路蛋白的相互作用,提示其参与基因组稳定性维持。

**建议**:实际研究中建议通过以下方式获取文献:

- 在PubMed检索“C7orf50 AND (antibody OR immunohistochemistry)”

- 查阅抗体公司(如Abcam、Sigma-Aldrich)的产品说明书引用文献

- 追踪UniProt数据库(Entry: Q9HCN9)中列出的相关研究。

       

背景信息

The C7orf50 antibody is a research tool designed to target the protein encoded by the **C7orf50 gene** (Chromosome 7 Open Reading Frame 50), a poorly characterized human gene located on chromosome 7. While the precise biological function of C7orf50 remains unclear, it is hypothesized to play roles in cellular processes such as transcriptional regulation, protein-protein interactions, or signaling pathways, based on conserved structural motifs and limited experimental data. The gene is ubiquitously expressed across tissues, suggesting potential housekeeping functions.

C7orf50 antibodies are typically developed in immunized animal models (e.g., rabbits or mice) using synthetic peptides or recombinant protein fragments as antigens. These antibodies enable the detection, localization, and quantification of C7orf50 protein in applications like Western blotting, immunofluorescence, or immunohistochemistry. Their specificity is often validated using knockout cell lines or siRNA-mediated gene silencing to confirm target binding.

Interest in C7orf50 has grown due to its implied associations with diseases, including cancer and neurodegenerative disorders, though evidence remains preliminary. For example, genomic studies link C7orf50 dysregulation to tumor progression or neurodevelopmental anomalies, but mechanistic insights are lacking. Researchers use C7orf50 antibodies to explore its expression patterns, subcellular distribution, and interaction partners, aiming to clarify its physiological and pathological roles. Despite limited data, such antibodies are critical for advancing functional studies of this enigmatic protein.

       
C7orf50抗体;C7orf50;C7orf50 Antibody;

公司简介

生物技术有限公司

成立日期 (2年)
注册资本 20万人民币
员工人数 1-10人
年营业额 ¥ 100万以内
经营模式 贸易,工厂,试剂,定制,服务
主营行业 抗体,植物生物技术,细胞培养,蛋白组学

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