SLC25A39抗体;SLC25A39 Antibody—艾普蒂

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     The image is immunohistochemistry of paraffin-embedded Human prostate cancer tissue using P13800(SLC25A39 Antibody) at dilution 1/50. (Original magnification: ×200)    

  
  

SLC25A39 is a member of the mitochondrial solute carrier family (SLC25), which plays critical roles in transporting metabolites across the mitochondrial inner membrane. Although its precise substrate specificity remains under investigation, SLC25A39 has been implicated in mitochondrial iron homeostasis and glutathione metabolism. Studies suggest it may regulate iron availability for heme biosynthesis or iron-sulfur cluster assembly, potentially linking it to cellular redox balance and mitochondrial function. Dysregulation of SLC25A39 has been associated with iron-related disorders, neurodegenerative diseases, and cancer progression.

SLC25A39 antibodies are essential tools for studying the protein's expression, localization, and molecular interactions. These antibodies enable detection via techniques like Western blotting, immunohistochemistry, and immunofluorescence, helping researchers map its tissue distribution and subcellular compartmentalization. Recent studies utilizing SLC25A39 antibodies have revealed its involvement in stress responses, including mitochondrial fragmentation under iron depletion. Knockout models combined with antibody validation have further highlighted its role in erythroid development and neuronal survival. Commercial SLC25A39 antibodies are typically raised against conserved peptide sequences, with validation often including gene silencing or knockout controls to confirm specificity. Ongoing research continues to clarify its biological functions and therapeutic potential in metabolic diseases.