FAM91A1抗体;FAM91A1 Antibody—艾普蒂

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     The image is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using P13390(FAM91A1 Antibody) at dilution 1/35. (Original magnification: ×200)    

  
  

FAM91A1 (Family with sequence similarity 91 member A1) is a protein-coding gene whose precise biological functions remain under investigation. It is implicated in intracellular trafficking and membrane dynamics, potentially interacting with components of the WASH/SCAR complex, which regulates actin polymerization and endosomal sorting. FAM91A1 is thought to play a role in maintaining Golgi apparatus integrity and facilitating vesicular transport, though its exact mechanisms are not fully elucidated.

Antibodies targeting FAM91A1 are essential tools for studying its expression, localization, and molecular interactions. These antibodies are typically developed in hosts like rabbits or mice using immunogenic peptides or recombinant protein fragments. They enable applications such as Western blotting, immunofluorescence, and immunoprecipitation, aiding in the detection of FAM91A1 in various cell types and tissues. Validation often includes knockout controls to confirm specificity.

Research utilizing FAM91A1 antibodies has explored its potential involvement in cellular processes like autophagy, cytokinesis, and neuronal development. Dysregulation of FAM91A1 has been tentatively linked to pathologies, including neurodevelopmental disorders and cancer, though further studies are needed. As interest in membrane trafficking pathways grows, FAM91A1 antibodies remain critical for unraveling its functional roles in health and disease.