C14orf180抗体;C14orf180 Antibody—艾普蒂

+ +

•  

   

     The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using P13376(C14orf180 Antibody) at dilution 1/30. (Original magnification: ×200)    

  
  

The C14orf180 antibody is a research tool designed to target the protein encoded by the *C14orf180* gene (Chromosome 14 Open Reading Frame 180), a poorly characterized human gene located on chromosome 14. This gene, also annotated as *CABIN1* or *KIAA0330* in some databases, is thought to encode a protein involved in cellular processes such as transcriptional regulation, calcium signaling, or immune modulation, though its precise biological functions remain unclear. The encoded protein contains conserved structural domains, including potential phosphorylation sites and nuclear localization signals, suggesting roles in intracellular signaling or nuclear activity.

C14orf180 antibodies are typically developed as polyclonal or monoclonal reagents for applications like Western blotting, immunohistochemistry, or immunofluorescence to detect endogenous protein expression in tissues or cell lines. Their utility lies in exploring the protein's localization, expression patterns, and potential interactions in health and disease. Limited studies have linked C14orf180 to immune responses, cancer progression, or neurological disorders, but further validation is needed. Researchers often use these antibodies in exploratory studies to elucidate the gene's function, though specificity and cross-reactivity challenges require careful experimental controls. Commercial antibodies may vary in validation rigor, emphasizing the need for peer-reviewed data to confirm reliability. Overall, C14orf180 antibodies serve as critical tools for unraveling the enigmatic roles of this understudied protein.