ENOSF1抗体;ENOSF1 Antibody—艾普蒂

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     The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using P13324(ENOSF1 Antibody) at dilution 1/20. (Original magnification: ×200)    

  
  

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     The image is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using P13324(ENOSF1 Antibody) at dilution 1/20. (Original magnification: ×200)    

  
  

The ENOSF1 (Enolase Superfamily Member 1) gene encodes a protein belonging to the enolase superfamily, which is involved in diverse metabolic pathways. While enolases are classically known for their role in glycolysis, ENOSF1 exhibits distinct functional characteristics. It is implicated in catalyzing reactions in specialized pathways, such as the metabolism of small molecules, though its precise biochemical role remains under investigation. Studies suggest ENOSF1 may interact with mitochondrial enzymes, influencing cellular energy homeostasis and oxidative stress responses.

ENOSF1 antibodies are essential tools for detecting and characterizing the protein's expression, localization, and interactions in biological samples. They are widely used in techniques like Western blotting, immunohistochemistry, and immunofluorescence to study ENOSF1's tissue distribution and dysregulation in diseases. For instance, ENOSF1 has been linked to cancer progression, with altered expression observed in colorectal, breast, and gastric cancers, suggesting potential roles as a biomarker or therapeutic target. Additionally, ENOSF1 variants are associated with rare genetic disorders, including mitochondrial encephalopathies, highlighting its importance in cellular metabolism.

Research using ENOSF1 antibodies has advanced understanding of its dual cytoplasmic and mitochondrial localization, hinting at multifaceted roles in cellular physiology. Ongoing studies aim to clarify its molecular mechanisms and therapeutic relevance in metabolic and neoplastic diseases.