TMEM192抗体;TMEM192 Antibody—艾普蒂

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     Gel: 12%SDS-PAGE, Lysate: 40 μg, Lane 1-2: A172 cell and Human liver tissue lysates, Primary antibody: P13317(TMEM192 Antibody) at dilution 1/300, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 30 seconds    

  
  

The TMEM192 (Transmembrane Protein 192) antibody is a tool used to study the expression and function of the TMEM192 protein, a poorly characterized member of the transmembrane protein family. TMEM192 is implicated in lysosomal biology, with studies suggesting its role in lysosomal membrane integrity, ion transport, or pH regulation. Its precise molecular function remains unclear, but it has been identified as a potential lysosomal marker due to its enrichment in lysosome-related cellular compartments.

TMEM192 antibodies are primarily utilized in research applications such as Western blotting, immunofluorescence, and immunoprecipitation to localize the protein or assess its expression levels under varying conditions. Recent studies have explored TMEM192's involvement in diseases, including cancer and neurodegenerative disorders, where lysosomal dysfunction is a hallmark. For instance, altered TMEM192 expression has been observed in certain cancers, suggesting its potential as a biomarker or therapeutic target.

Despite its growing research relevance, challenges persist in characterizing TMEM192 due to limited structural and functional data. Commercial antibodies vary in specificity, requiring rigorous validation to avoid cross-reactivity with unrelated proteins. Ongoing work aims to clarify TMEM192's interactions within lysosomal networks and its broader physiological roles, driving demand for reliable antibodies to advance mechanistic studies.