AHCTF1抗体;AHCTF1 Antibody—艾普蒂 新品

The AHCTF1 antibody is a research tool designed to detect AHCTF1 (also known as ELYS or MSTP118), a critical protein involved in nuclear envelope reformation and mitotic spindle assembly during cell division. AHCTF1 plays a key role in recruiting essential components, such as the Nup107-160 complex, to chromatin during late mitosis, facilitating nuclear pore complex assembly and nucleocytoplasmic transport. It is also implicated in chromatin organization and regulation of gene expression. Dysregulation of AHCTF1 has been linked to genomic instability, developmental defects, and cancer progression. Researchers use AHCTF1 antibodies in techniques like Western blotting, immunofluorescence, and immunohistochemistry to study its localization, expression levels, and interactions in cellular processes. These studies help elucidate AHCTF1’s role in cell cycle regulation, cancer biology, and potential therapeutic targeting. The antibody’s specificity and validation across experimental models make it valuable for both basic and translational research aimed at understanding mechanisms underlying mitotic fidelity and disease pathogenesis.