CYB5D1抗体;CYB5D1 Antibody—艾普蒂

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     Gel: 12%SDS-PAGE, Lysate: 40 μg, Lane 1-5: Hela, PC-3, A549, 293T and 231 cell lysates, Primary antibody: P13220(CYB5D1 Antibody) at dilution 1/300, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute    

  
  

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     The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using P13220(CYB5D1 Antibody) at dilution 1/20. (Original magnification: ×200)    

  
  

The CYB5D1 antibody is a research tool designed to detect and study cytochrome b5 domain-containing protein 1 (CYB5D1), a member of the cytochrome b5 family. This protein is characterized by a conserved cytochrome b5-like heme-binding domain, though its precise physiological role remains less understood compared to other family members like CYB5A or CYB5R. CYB5D1 is hypothesized to participate in redox reactions, lipid metabolism, or cellular detoxification processes, potentially interacting with cytochrome P450 enzymes. Its expression has been observed in various tissues, including the liver, brain, and reproductive organs, suggesting tissue-specific functions.

CYB5D1 antibodies are typically developed in hosts such as rabbits or mice, using immunogens derived from specific CYB5D1 peptide sequences or recombinant proteins. These antibodies enable researchers to investigate CYB5D1's expression patterns, subcellular localization (e.g., endoplasmic reticulum or mitochondrial associations), and interactions via techniques like Western blotting, immunohistochemistry, or immunofluorescence. Studies using CYB5D1 antibodies may explore its role in diseases linked to metabolic dysregulation, cancer, or neurodegenerative disorders. However, limited literature and the lack of comprehensive functional studies highlight the need for further validation of CYB5D1's biological significance and the antibody's specificity. Commercial availability varies, with some suppliers offering monoclonal or polyclonal options for experimental use.