ACER1抗体;ACER1 Antibody—艾普蒂 新品

The ACER1 (alkaline ceramidase 1) antibody is a tool used to study the ACER1 protein, a key enzyme in sphingolipid metabolism. ACER1. encoded by the *ACER1* gene, belongs to the alkaline ceramidase family and hydrolyzes ceramide into sphingosine and free fatty acids, regulating cellular levels of these bioactive lipids. Ceramide and its metabolites influence critical processes like apoptosis, proliferation, and differentiation. ACER1 is predominantly expressed in the skin, intestines, and reproductive tissues, and its dysfunction has been linked to pathologies such as leukodystrophy, neurodegenerative disorders, and cancer. Researchers employ ACER1 antibodies in techniques like Western blotting, immunohistochemistry, and immunofluorescence to detect protein expression, localization, and alterations in disease models. These antibodies aid in elucidating ACER1's role in lipid signaling pathways, its interaction with cellular stress responses, and potential therapeutic targets. Commercial ACER1 antibodies are typically validated for specificity and sensitivity across species, with applications in both basic research and clinical investigations, particularly in studies exploring sphingolipid-related diseases or cancer biology.