ARCN1抗体;ARCN1 Antibody—艾普蒂 新品

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     The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using P13103(ARCN1 Antibody) at dilution 1/50. (Original magnification: ×200)    

  
  

The ARCN1 antibody targets the Archain 1 (ARCN1) protein, a subunit of the coatomer protein complex I (COPI), which plays a critical role in intracellular vesicle trafficking. COPI-coated vesicles mediate retrograde transport of proteins and lipids within the Golgi apparatus and between the Golgi and endoplasmic reticulum. ARCN1 is essential for maintaining Golgi structure and function, ensuring proper protein sorting, modification, and secretion. Dysregulation of ARCN1 has been linked to cellular stress, disrupted protein homeostasis, and diseases such as cancer and developmental disorders.

ARCN1 antibodies are widely used in research to study COPI complex dynamics, intracellular transport mechanisms, and ARCN1’s role in pathological conditions. These antibodies enable detection of ARCN1 expression levels, subcellular localization (e.g., via immunofluorescence or immunohistochemistry), and interactions with other COPI subunits (e.g., through co-immunoprecipitation). In cancer research, ARCN1 antibodies help investigate its overexpression in certain tumors, where it may promote proliferation or metastasis. Additionally, ARCN1 is considered a housekeeping gene in some contexts, making its antibody a tool for normalizing experimental data.

Recent studies also explore ARCN1’s potential as a biomarker or therapeutic target, highlighting the antibody’s utility in both basic and translational research. Its cross-reactivity with homologs in model organisms further supports comparative studies in cell biology and disease mechanisms.