XIRP1抗体;XIRP1 Antibody—艾普蒂

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     The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using P12869(XIRP1 Antibody) at dilution 1/35. (Original magnification: ×200)    

  
  

The XIRP1 (Xin Actin-Binding Repeat Containing Protein 1) antibody is a tool used to study the role of XIRP1. a protein predominantly expressed in cardiac and skeletal muscle tissues. XIRP1. also known as Xin, is critical for maintaining structural and functional integrity in striated muscles. It contains multiple Xin repeats that mediate interactions with actin filaments, facilitating cytoskeletal organization, cell adhesion, and mechanotransduction. XIRP1 is implicated in myofibril assembly, muscle regeneration, and intercalated disc formation in cardiomyocytes, making it essential for normal cardiac development and function.

Antibodies targeting XIRP1 are widely utilized in research to investigate its expression, localization, and molecular interactions. They enable techniques like Western blotting, immunofluorescence, and immunohistochemistry to visualize XIRP1 distribution in tissues and assess its involvement in muscle-related pathologies. Studies have linked XIRP1 dysregulation to cardiovascular diseases, including cardiomyopathies, arrhythmias, and muscular dystrophies, highlighting its potential as a biomarker or therapeutic target. Additionally, XIRP1 antibodies aid in exploring its role in developmental biology and regenerative processes. Commercial XIRP1 antibodies are typically validated for specificity, often targeting conserved regions like the Xin repeats. Ongoing research continues to unravel its signaling pathways and interactions with proteins such as β-catenin and vinculin, expanding understanding of muscle biology and disease mechanisms.