MATN2抗体;MATN2 Antibody—艾普蒂

The MATN2 antibody is a research tool designed to detect matrilin-2 (MATN2), a protein belonging to the matrilin family of extracellular matrix (ECM) components. Matrilins are involved in ECM assembly, tissue development, and cellular interactions, with MATN2 specifically expressed in tissues like cartilage, heart, and blood vessels. It plays roles in modulating cell adhesion, signaling, and tissue remodeling by interacting with other ECM proteins, such as collagen and proteoglycans. MATN2 antibodies are commonly used in studies investigating musculoskeletal disorders, cardiovascular diseases, or cancer, where ECM dysregulation is implicated. These antibodies enable detection of MATN2 expression patterns via techniques like Western blot, immunohistochemistry, or immunofluorescence. Recent studies highlight MATN2's potential involvement in tumor progression, fibrosis, and cartilage repair, making its antibody a valuable tool for mechanistic and diagnostic research. However, commercial availability and validation data vary, requiring careful selection based on target epitopes, species reactivity (human, mouse, etc.), and application-specific performance. Ongoing research continues to explore MATN2's functional diversity and therapeutic relevance.