LRRC49抗体;LRRC49 Antibody—艾普蒂

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     The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using P12778(LRRC49 Antibody) at dilution 1/40. (Original magnification: ×200)    

  
  

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     The image is immunohistochemistry of paraffin-embedded Human brain tissue using P12778(LRRC49 Antibody) at dilution 1/40. (Original magnification: ×200)    

  
  

The LRRC49 (Leucine-Rich Repeat-Containing Protein 49) antibody is a research tool designed to detect and study the LRRC49 protein, a member of the leucine-rich repeat (LRR) superfamily. LRR proteins are characterized by repetitive structural motifs involved in protein-protein interactions, cellular signaling, and molecular recognition. LRRC49. encoded by the *LRRC49* gene, is a relatively understudied protein, though its structural features suggest potential roles in immune regulation, cell adhesion, or developmental processes.

Current research indicates that LRRC49 may be expressed in specific tissues, such as the testes, where it could participate in spermatogenesis or sperm function. Its LRR domains might mediate interactions with other proteins or ligands, influencing intracellular pathways. However, its precise biological functions and mechanisms remain unclear, necessitating further investigation.

The LRRC49 antibody, often developed in rabbits or mice as polyclonal or monoclonal variants, is primarily used in applications like Western blotting, immunohistochemistry (IHC), or immunofluorescence (IF) to map protein expression patterns and localization. It serves as a critical reagent for validating *LRRC49* gene knockout models or exploring its association with diseases, including infertility or cancers. Commercial availability of this antibody supports basic research, but validation for specificity and cross-reactivity is essential due to the conserved nature of LRR motifs across proteins.

Overall, LRRC49 antibodies are pivotal in unraveling the protein’s physiological and pathological relevance, bridging gaps in understanding its role in cellular processes.